薰衣草（Lavandula stoechas ssp. stoechas）根中的三萜类化合物。

Triterpenoids of the roots of Lavandula stoechas ssp. stoechas.

作者信息

Topçu G, Ayral M N, Aydin A, Gören A C, Chai H B, Pezzuto J M

机构信息

Faculty of Pharmacy, University of Istanbul.

出版信息

Pharmazie. 2001 Nov;56(11):892-5.

PMID:11817178

Abstract

The roots of Lavandula stoechas ssp. stoechas afforded eleven known triterpenes, two steroids and two aromatics, in addition to two new triterpenes, 18-hydroxy-27-norolean-12,14-dien-30-al-28-oic acid and 3 beta-hydroxy-1-oxo-olean-12-ene-30-al-28-oic acid. Their structures were determined by spectroscopic analyses. The chloroform extract and some isolated compounds were evaluated for their growth inhibitory activity against several mammalian cell lines.

摘要

西班牙薰衣草亚种西班牙薰衣草的根除了产生两种新的三萜类化合物，即18-羟基-27-降齐墩果-12,14-二烯-30-醛-28-酸和3β-羟基-1-氧代-齐墩果-12-烯-30-醛-28-酸外，还提供了11种已知的三萜类化合物、两种甾体化合物和两种芳香族化合物。通过光谱分析确定了它们的结构。对氯仿提取物和一些分离出的化合物进行了针对几种哺乳动物细胞系的生长抑制活性评估。