正中神经刺激期间人类初级体感皮层和运动皮层的功能磁共振成像
Functional MRI of human primary somatosensory and motor cortex during median nerve stimulation.
作者信息
Spiegel J, Tintera J, Gawehn J, Stoeter P, Treede R D
机构信息
Institute of Physiology and Pathophysiology, Johannes Gutenberg-University, Mainz, Germany.
出版信息
Clin Neurophysiol. 1999 Jan;110(1):47-52. doi: 10.1016/s0168-5597(98)00043-4.
OBJECTIVES
Somatosensory evoked potential (SEP) studies suggested that some early cortical SEP components may be generated in the primary motor cortex (M1) rather than the primary somatosensory cortex (S1).
METHODS
We now used functional magnetic resonance imaging (fMRI) to study activation of S1 and M1 by electrical median nerve stimulation in healthy volunteers.
RESULTS
The hand areas of both S1 and M1 showed significant activation (correlation coefficients >0.45) in 7 of 9 subjects (activated volume S1 > M1). For comparison, a sequential finger opposition task significantly activated S1 in 7 and M1 in all 9 subjects (activated volume M1 > S1).
CONCLUSIONS
These data show that the electrical stimuli used for SEP recording lead to a functional activation of S1 as well as M1.
目的
体感诱发电位（SEP）研究表明，一些早期皮质SEP成分可能是在初级运动皮层（M1）而非初级体感皮层（S1）产生的。
方法
我们现在使用功能磁共振成像（fMRI）来研究健康志愿者中电刺激正中神经时S1和M1的激活情况。
结果
在9名受试者中的7名中，S1和M1的手部区域均显示出显著激活（相关系数>0.45）（激活体积S1>M1）。作为对照，一项连续的手指对指任务在7名受试者中显著激活了S1，在所有9名受试者中均显著激活了M1（激活体积M1>S1）。
结论
这些数据表明，用于SEP记录的电刺激会导致S1和M1的功能激活。
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