García-Hidalgo L, Orozco-Topete R, Gonzalez-Barranco J, Villa A R, Dalman J J, Ortiz-Pedroza G
Department of Dermatology, Instituto Nacional de la Nutrición Salvador Zubirán, México City, México.
Obes Res. 1999 May;7(3):299-302. doi: 10.1002/j.1550-8528.1999.tb00410.x.
Skin diseases are mentioned as a frequent finding in the obese patient. However, to our knowledge no study has been done on this subject.
To determine the prevalence of skin diseases associated with different obesity grades and if any dermatosis can be considered an obesity marker.
A cross-sectional study of 156 obese patients who were 110% to 293% overweight were included. Complete medical history and dermatological examination were done.
In the 126 female and 30 male obese patients, grades I to V, with a body mass index (BMI) of 27-51, cutaneous findings with statistical significance for linear trend were: plantar hyperkeratosis 54 patients p = 0.00001; acanthosis nigricans 46 patients p = 0.00005; striae 67 patients p = 0.03; skin tags 69 patients p = 0.01; keratosis pilaris 33 patients p = 0.007. Patients with plantar hyperkeratosis were distributed in the obesity groups as follows: grade I = 3 patients; grade II = 7 patients; grade III = 8 patients; grade IV = 17 patients; and grade V = 19 patients. Of the 76 diabetic patients, 26 had acanthosis nigricans, 38 had skin tags, and 27 had plantar hyperkeratosis.
Plantar hyperkeratosis should be considered as a cutaneous stigma of severe obesity. This is probably a result of pressure directly related to the excess weight.
皮肤疾病在肥胖患者中是常见症状。然而,据我们所知,尚未有关于该主题的研究。
确定与不同肥胖等级相关的皮肤疾病患病率,以及是否有任何皮肤病可被视为肥胖标志物。
纳入156例超重110%至293%的肥胖患者进行横断面研究。进行了完整的病史采集和皮肤科检查。
在126名女性和30名男性肥胖患者中,I至V级,体重指数(BMI)为27 - 51,具有线性趋势统计学意义的皮肤表现为:足底角化过度54例,p = 0.00001;黑棘皮病46例,p = 0.00005;萎缩纹67例,p = 0.03;皮赘69例,p = 0.01;毛发角化病33例,p = 0.007。足底角化过度患者在肥胖组中的分布如下:I级 = 3例;II级 = 7例;III级 = 8例;IV级 = 17例;V级 = 19例。在76例糖尿病患者中,26例有黑棘皮病,38例有皮赘,27例有足底角化过度。
足底角化过度应被视为严重肥胖的皮肤特征。这可能是与超重直接相关的压力所致。