Darlenski Razvigor, Mihaylova Vesselina, Handjieva-Darlenska Teodora
Department of Dermatology and Venereology, Acibadem Cityclinic Tokuda Hospital, Sofia, Bulgaria.
Department of Dermatology and Venereology, Trakia University, Stara Zagora, Bulgaria.
Front Nutr. 2022 Mar 10;9:855573. doi: 10.3389/fnut.2022.855573. eCollection 2022.
Obesity as a multi-organ disease that affects the entire human organism. Notably, the skin is no exclusion from this postulate. Skin changes in obese patients have been widely studied with regards to mechanical friction, skin infections, and skin hypertrophic conditions, such as acanthosis nigricans and, most commonly, fibromas (skin tags). Almost 60-70% of obese patients present with a variety of skin changes. Herein, we discuss our own experience and review the complex skin changes in obesity. The role of metabolic syndrome and obesity are responsible for the epidemiological prevalence and are involved in the pathogenesis of chronic inflammatory skin diseases, such as psoriasis, atopic dermatitis, and skin malignancies. Here, we comment on the role of nutritional interventions in these patients as it has been proven that low-calorie diet and weight loss is related to improvement of inflammatory skin diseases. The readership of this paper will receive up-to-date overview on the connection between obesity and the skin that is of a practical importance to any clinician working in the field.
肥胖是一种影响整个人体的多器官疾病。值得注意的是，皮肤也不例外。肥胖患者的皮肤变化在机械摩擦、皮肤感染以及皮肤肥厚性疾病方面，如黑棘皮病，最常见的是纤维瘤（皮赘），都得到了广泛研究。近60%至70%的肥胖患者存在各种皮肤变化。在此，我们讨论自身经验并综述肥胖患者复杂的皮肤变化。代谢综合征和肥胖的作用导致了流行病学上的患病率，且参与了慢性炎症性皮肤病，如银屑病、特应性皮炎和皮肤恶性肿瘤的发病机制。在此，我们评论营养干预在这些患者中的作用，因为已证实低热量饮食和体重减轻与炎症性皮肤病的改善有关。本文的读者将获得有关肥胖与皮肤之间联系的最新综述，这对该领域的任何临床医生都具有实际重要性。
