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Preparation and characterization of carmustine loaded polyanhydride wafers for treating brain tumors.

作者信息

Domb A J, Israel Z H, Elmalak O, Teomim D, Bentolila A

机构信息

Department of Neurosurgery, Hadassah University Hospital, Jerusalem, Israel.

出版信息

Pharm Res. 1999 May;16(5):762-5. doi: 10.1023/a:1011995728760.

DOI:10.1023/a:1011995728760
PMID:10350022
Abstract
摘要

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Preparation and characterization of carmustine loaded polyanhydride wafers for treating brain tumors.
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Excretion of a radiolabelled anticancer biodegradable polymeric implant from the rabbit brain.放射性标记的可生物降解抗癌聚合物植入物从兔脑中的排泄情况。
Biomaterials. 1995 Sep;16(14):1069-72. doi: 10.1016/0142-9612(95)98902-q.
3
Role of convective flow in carmustine delivery to a brain tumor.对流在卡莫司汀递送至脑肿瘤中的作用。
Pharm Res. 2009 Oct;26(10):2289-302. doi: 10.1007/s11095-009-9945-8. Epub 2009 Jul 29.
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Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors.优化从控释聚合物中递送卡莫司汀用于治疗脑肿瘤的间质给药方式。
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本文引用的文献

1
Pharmacokinetics of interstitial delivery of carmustine, 4-hydroperoxycyclophosphamide, and paclitaxel from a biodegradable polymer implant in the monkey brain.卡莫司汀、4-氢过氧环磷酰胺和紫杉醇从可生物降解聚合物植入物在猴脑间质给药的药代动力学。
Cancer Res. 1998 Feb 15;58(4):672-84.
2
Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors.优化从控释聚合物中递送卡莫司汀用于治疗脑肿瘤的间质给药方式。
Cancer Chemother Pharmacol. 1997;39(5):383-9. doi: 10.1007/s002800050588.
3
Morphological characterization of polyanhydride biodegradable implant gliadel during in vitro and in vivo erosion using scanning electron microscopy.
用于抑制血小板功能的阿司匹林多不饱和脂肪酸衍生物的研发。
J Pharmacol Exp Ther. 2016 Oct;359(1):134-41. doi: 10.1124/jpet.116.234781. Epub 2016 Aug 3.
4
Self-assembly of cytotoxic peptide amphiphiles into supramolecular membranes for cancer therapy.细胞毒性肽两亲物自组装成超分子膜用于癌症治疗。
Adv Healthc Mater. 2013 Jan;2(1):126-33. doi: 10.1002/adhm.201200118. Epub 2012 Jul 31.
5
Polifeprosan 20, 3.85% carmustine slow-release wafer in malignant glioma: evidence for role in era of standard adjuvant temozolomide.聚乙二醇丙交酯-乙交酯共聚物20，含3.85%卡莫司汀缓释晶片用于恶性胶质瘤：在标准辅助替莫唑胺时代的作用证据
Core Evid. 2012;7:115-30. doi: 10.2147/CE.S23244. Epub 2012 Oct 26.
6
Advanced drug delivery systems of curcumin for cancer chemoprevention.姜黄素用于癌症化学预防的先进药物传递系统。
Cancer Prev Res (Phila). 2011 Aug;4(8):1158-71. doi: 10.1158/1940-6207.CAPR-10-0006. Epub 2011 May 5.
7
Anhydride prodrug of ibuprofen and acrylic polymers.布洛芬的酸酐前药与丙烯酸聚合物
AAPS PharmSciTech. 2009;10(2):453-8. doi: 10.1208/s12249-009-9228-z. Epub 2009 Apr 21.
8
Characterization and in vitro degradation of poly(octadecanoic anhydride).聚十八烷酸酐的表征及体外降解
J Mater Sci Mater Med. 2008 Jan;19(1):39-46. doi: 10.1007/s10856-007-3166-7. Epub 2007 Jun 19.
9
Electrospun micro- and nanofibers for sustained delivery of paclitaxel to treat C6 glioma in vitro.用于将紫杉醇持续递送至体外治疗C6胶质瘤的电纺微米和纳米纤维。
Pharm Res. 2006 Aug;23(8):1817-26. doi: 10.1007/s11095-006-9036-z.
10
Anhydride prodrugs for nonsteroidal anti-inflammatory drugs.用于非甾体抗炎药的酸酐前药
Pharm Res. 2003 Feb;20(2):205-11. doi: 10.1023/a:1022214919481.
使用扫描电子显微镜对聚酸酐生物可降解植入物Gliadel在体外和体内侵蚀过程中的形态学特征进行表征。
Pharm Res. 1996 May;13(5):683-91. doi: 10.1023/a:1016035229961.
4
Interstitial chemotherapy of the 9L gliosarcoma: controlled release polymers for drug delivery in the brain.9L胶质肉瘤的间质化疗：用于脑部药物递送的控释聚合物
Cancer Res. 1993 Jan 15;53(2):329-33.
5
Biodegradable polymers for controlled delivery of chemotherapy with and without radiation therapy in the monkey brain.用于在猴脑中有或无放射治疗情况下进行化疗药物控释的可生物降解聚合物。
J Neurosurg. 1994 Feb;80(2):283-90. doi: 10.3171/jns.1994.80.2.0283.
6
Metabolic disposition and elimination studies of a radiolabelled biodegradable polymeric implant in the rat brain.
Biomaterials. 1994 Jul;15(9):681-8. doi: 10.1016/0142-9612(94)90166-x.
7
Interstitial taxol delivered from a biodegradable polymer implant against experimental malignant glioma.从可生物降解聚合物植入物中递送的间质紫杉醇用于对抗实验性恶性胶质瘤。
Cancer Res. 1994 Apr 15;54(8):2207-12.
8
Erosion of a new family of biodegradable polyanhydrides.一类新型可生物降解聚酸酐的侵蚀
J Biomed Mater Res. 1994 Dec;28(12):1465-75. doi: 10.1002/jbm.820281212.
9
Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas.环磷酰胺衍生物与聚合物控释对大鼠胶质瘤的有效性。
J Neurosurg. 1995 Mar;82(3):481-6. doi: 10.3171/jns.1995.82.3.0481.
10
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group.可生物降解聚合物术中控制释放化疗药物治疗复发性胶质瘤安全性和有效性的安慰剂对照试验。聚合物-脑肿瘤治疗组。
Lancet. 1995 Apr 22;345(8956):1008-12. doi: 10.1016/s0140-6736(95)90755-6.