• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Molecular bases for the recognition of tyrosine-based sorting signals.

作者信息

Bonifacino J S, Dell'Angelica E C

机构信息

Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

出版信息

J Cell Biol. 1999 May 31;145(5):923-6. doi: 10.1083/jcb.145.5.923.

DOI:10.1083/jcb.145.5.923
PMID:10352010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2133128/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c10/2133128/e90851d302f8/JCB9904075.f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c10/2133128/e90851d302f8/JCB9904075.f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c10/2133128/e90851d302f8/JCB9904075.f1.jpg

相似文献

1
Molecular bases for the recognition of tyrosine-based sorting signals.基于酪氨酸的分选信号识别的分子基础。
J Cell Biol. 1999 May 31;145(5):923-6. doi: 10.1083/jcb.145.5.923.
2
Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells.极化上皮细胞中AP-1B亚基μ1B对基于酪氨酸的基底外侧信号的差异识别。
Mol Biol Cell. 2002 Jul;13(7):2374-82. doi: 10.1091/mbc.e01-10-0096.
3
Recognition of sorting signals by clathrin adaptors.网格蛋白衔接蛋白对分选信号的识别。
Bioessays. 1999 Jul;21(7):558-67. doi: 10.1002/(SICI)1521-1878(199907)21:7<558::AID-BIES4>3.0.CO;2-R.
4
Differential recognition of a tyrosine-dependent signal in the basolateral and endocytic pathways of thyroid epithelial cells.甲状腺上皮细胞基底外侧和内吞途径中酪氨酸依赖性信号的差异识别。
Endocrinology. 2002 Apr;143(4):1291-301. doi: 10.1210/endo.143.4.8734.
5
Mechanisms of signal-mediated protein sorting in the endocytic and secretory pathways.内吞和分泌途径中信号介导的蛋白质分选机制。
Proc Assoc Am Physicians. 1996 Jul;108(4):285-95.
6
Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable components.基于酪氨酸和双亮氨酸信号的蛋白质靶向：不同饱和成分的证据
J Cell Biol. 1996 Oct;135(2):341-54. doi: 10.1083/jcb.135.2.341.
7
The tyrosine-based lysosomal targeting signal in lamp-1 mediates sorting into Golgi-derived clathrin-coated vesicles.Lamp-1中基于酪氨酸的溶酶体靶向信号介导其被分选到源自高尔基体的网格蛋白包被小泡中。
EMBO J. 1996 Oct 1;15(19):5230-9.
8
[Protein tyrosine nitration and cell signal transduction].[蛋白质酪氨酸硝化作用与细胞信号转导]
Sheng Li Ke Xue Jin Zhan. 2007 Oct;38(4):369-72.
9
Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless.催乳素通过信号蛋白SHC、生长因子受体结合蛋白2和七号染色体失活蛋白的同源物激活Ras。
Endocrinology. 1995 Aug;136(8):3512-8. doi: 10.1210/endo.136.8.7628388.
10
Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes.网格蛋白AP-2复合物识别基于酪氨酸的内吞信号的序列要求。
EMBO J. 1996 Nov 1;15(21):5789-95.

引用本文的文献

1
Restoring adapter protein complex 4 function with small molecules: an in silico approach to spastic paraplegia 50.用小分子恢复衔接蛋白复合体4的功能：针对痉挛性截瘫50型的计算机模拟方法
Protein Sci. 2025 Jan;34(1):e70006. doi: 10.1002/pro.70006.
2
Required minimal protein domain of flower for synaptobrevin2 endocytosis in cytotoxic T cells.细胞毒性T细胞中用于突触融合蛋白2内吞作用的花所需最小蛋白结构域。
Cell Mol Life Sci. 2024 Dec 18;82(1):8. doi: 10.1007/s00018-024-05528-1.
3
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity.

本文引用的文献

1
Protein sorting by tyrosine-based signals: adapting to the Ys and wherefores.基于酪氨酸信号的蛋白质分拣：适应 Ys 及其来龙去脉。
Trends Cell Biol. 1997 Mar;7(3):124-8. doi: 10.1016/S0962-8924(96)10057-X.
2
Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells.Mu1B，一种在极化上皮细胞中表达的新型衔接子中链。
FEBS Lett. 1999 Apr 23;449(2-3):215-20. doi: 10.1016/s0014-5793(99)00432-9.
3
Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis.
嵌合抗原受体（CAR）细胞效应器的谱系：抗肿瘤免疫中的作用模式
Cancers (Basel). 2024 Jul 22;16(14):2608. doi: 10.3390/cancers16142608.
4
Sequence and structural insights of monoleucine-based sorting motifs contained within the cytoplasmic domains of basolateral proteins.位于基底外侧蛋白胞质结构域内的基于单亮氨酸的分选基序的序列和结构见解。
Front Cell Dev Biol. 2024 Mar 1;12:1379224. doi: 10.3389/fcell.2024.1379224. eCollection 2024.
5
AP-3 adaptor complex-mediated vesicle trafficking.AP-3衔接蛋白复合物介导的囊泡运输。
Biophys Rep. 2021 Apr 30;7(2):91-100. doi: 10.52601/bpr.2021.200051.
6
Emerging Landscape of Cell-Penetrating Peptide-Mediated Organelle Restoration and Replacement.细胞穿透肽介导的细胞器修复与替换的新进展
ACS Pharmacol Transl Sci. 2023 Jan 16;6(2):229-244. doi: 10.1021/acsptsci.2c00229. eCollection 2023 Feb 10.
7
AP-4 regulates neuronal lysosome composition, function, and transport via regulating export of critical lysosome receptor proteins at the trans-Golgi network.AP-4 通过调节跨高尔基网络中关键溶酶体受体蛋白的输出来调节神经元溶酶体的组成、功能和运输。
Mol Biol Cell. 2022 Oct 1;33(12):ar102. doi: 10.1091/mbc.E21-09-0473. Epub 2022 Aug 17.
8
How Viruses Hijack and Modify the Secretory Transport Pathway.病毒如何劫持和修饰分泌转运途径。
Cells. 2021 Sep 24;10(10):2535. doi: 10.3390/cells10102535.
9
Peptide-Based Nanoparticles for Therapeutic Nucleic Acid Delivery.用于治疗性核酸递送的肽基纳米颗粒。
Biomedicines. 2021 May 20;9(5):583. doi: 10.3390/biomedicines9050583.
10
Two Separate Tyrosine-Based YXXL/Φ Motifs within the Glycoprotein E Cytoplasmic Tail of Bovine Herpesvirus 1 Contribute in Virus Anterograde Neuronal Transport.牛疱疹病毒 1 糖蛋白 E 细胞质尾部内的两个独立的酪氨酸基 YXXL/Φ 基序有助于病毒顺行神经元运输。
Viruses. 2020 Sep 14;12(9):1025. doi: 10.3390/v12091025.
显性负性突变体μ2亚基对网格蛋白衔接蛋白AP-2受体结合功能的抑制作用及其对胞吞作用的影响。
EMBO J. 1999 May 4;18(9):2489-99. doi: 10.1093/emboj/18.9.2489.
4
AP-4, a novel protein complex related to clathrin adaptors.AP-4，一种与网格蛋白衔接蛋白相关的新型蛋白质复合物。
J Biol Chem. 1999 Mar 12;274(11):7278-85. doi: 10.1074/jbc.274.11.7278.
5
Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor.由于AP-3衔接蛋白β3A亚基的突变，导致Hermansky-Pudlak综合征中溶酶体蛋白转运改变。
Mol Cell. 1999 Jan;3(1):11-21. doi: 10.1016/s1097-2765(00)80170-7.
6
Interactions of the AP-1 Golgi adaptor with the polymeric immunoglobulin receptor and their possible role in mediating brefeldin A-sensitive basolateral targeting from the trans-Golgi network.AP-1高尔基体衔接蛋白与多聚免疫球蛋白受体的相互作用及其在介导从反式高尔基体网络向基底外侧靶向运输中对布雷菲德菌素A敏感的可能作用。
J Biol Chem. 1999 Jan 22;274(4):2201-15. doi: 10.1074/jbc.274.4.2201.
7
A structural explanation for the recognition of tyrosine-based endocytotic signals.基于酪氨酸的内吞信号识别的结构解释。
Science. 1998 Nov 13;282(5392):1327-32. doi: 10.1126/science.282.5392.1327.
8
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4.HIV-1 Nef中的双亮氨酸基序对于分选进入网格蛋白包被小窝以及下调CD4至关重要。
Curr Biol. 1998 Nov 5;8(22):1239-42. doi: 10.1016/s0960-9822(07)00518-0.
9
Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120.衔接蛋白复合物中链与TGN38和lgp120基于酪氨酸的分选基序之间相互作用的特异性
Biochem J. 1998 Nov 1;335 ( Pt 3)(Pt 3):567-72. doi: 10.1042/bj3350567.
10
The mammalian AP-3 adaptor-like complex mediates the intracellular transport of lysosomal membrane glycoproteins.哺乳动物AP-3衔接蛋白样复合物介导溶酶体膜糖蛋白的细胞内运输。
J Biol Chem. 1998 Nov 6;273(45):29451-61. doi: 10.1074/jbc.273.45.29451.