Rakić N
Opsta bolnica, Zdravstveni centar, Subotica.
Med Pregl. 1999 Jan-Feb;52(1-2):44-52.
Sudden sensorineural hearing loss is an acute hearing loss of a perceptive type, of unknown etiology, in most cases one-sided, or, a every sudden sensorineural deafness that occurs in the period of three days or less. Modern scientific literature points to three possible etiological factors: viral cochleitis, vascular lesion of the labyrinth and unrecognized rupture of the membranous labyrinth. The therapy for this disease is extremely various. There are dozens of reported different (or similar) healing protocols, including vasodilators, Hydroxyethyl starch, low molecular dextran, diuretics, defibrinogenation, fibrmolytic therapy, steroids, prostacyclin, oxygen therapy, hyperbaric oxygen therapy, vitamins, etc. The aim of the study was to recapitulate in brief modern views of etiology and therapy of the sudden sensorineural hearing loss, to analyze cases of this illness within the period of 1991-1996 in our Otorhinolaryngology Department and to compare these data with the same or similar data of other authors.
In this study, medical records of patients admitted in the period of 1991-1996 in the Otorhinolaryngology Department of the Health Center in Subotica with a diagnosis of sudden sensorineural hearing loss were used. There were 53 patients with this diagnosis. All patients were treated in the hospital with infusions of rheoactive drugs. During the diagnostic procedure, all patients underwent a complete clinical otorhinolaryngologic examination, detailed anamnesis was taken, acoustic impedance tests (tympanometry) and tonal liminal audiometry were performed. Routine blood test was made (including complete blood picture, sedimentation rate, blood sugar) and a complete urine examination. Sometimes we demanded x-ray of the temporal bones (Schnller and Stenwers). A short increment sensitivity index (SISI) test and Carhart test were also made, if necessary. Function of the vestibular system was tested in cases when the vestibular symptoms were more strongly expressed. This test was made after passing an acute attack of vertiginous symptoms. Control audiometry was made on the seventh and on the fourteenth day after admission. This therapy consisted of an infusion of physiologic solution (NaCl) 250 or 500 ml twice daily to which 300 mg xanthinol nicotinate ampulla, paracetam 1 g ampulla, dipyridamole 10 mg ampulla and C-vitamin 10% 500 mg ampulla were applied. The number of paracetam and xanthinol nicotinate ampullas was raised on the 14/day, and then it fell to the starting value. The therapy lasted 17 days. Patients were given multivitamine peroral therapy, tranquilizers and diet without coffee, smoking and allergenic food.
The study included 53 patients, 27 (50.94%) female and 26 (49.06%) males (Graph 1). Their age (Graph 2) ranged between 16-71 years. The biggest group of patients was between 40-49 (39.62%) years of age. Distribution per year (Graph 3) shows that the incidence of the acute sensorineural hearing loss differs from the findings of other authors, especially in the period of 1991-1994, due to very few cases. Connection of this illness with seasons is shown in Graph 4. We had most cases during summer time (August, 16.98%). There is a mild rise in winter (December, 13.21%). The degree of the hearing loss in decibels is shown in the Graph 5. Most of the patients (75.47%) had mild or severely damaged hearing (40-85 dB). Period of the deafness before patients were admitted to the hospital, is shown in Graph 7. Most of them came in the first seven days after they experienced acute deafness (52.83%). Symptomatology of the persons with acute hearing loss is shown in Table 1. All of them had the feeling of deafness, and 50.94% also had tinnitus. Table 2 shows that only two patients had a pathologic finding (hypo function) on the vestibular caloric test. 57.14% of patients tested by this method showed a normal function of the vestibular apparatus. The recovery of he
突发性感音神经性听力损失是一种急性的、病因不明的感知性听力损失,多数情况下为单侧性,或者是在三天或更短时间内发生的突发性感音神经性耳聋。现代科学文献指出了三种可能的病因:病毒性耳蜗炎、迷路的血管病变以及未被识别的膜迷路破裂。这种疾病的治疗方法多种多样。有数十种不同(或类似)的治疗方案被报道,包括血管扩张剂、羟乙基淀粉、低分子右旋糖酐、利尿剂、去纤维蛋白、纤维蛋白溶解疗法、类固醇、前列环素、氧疗、高压氧疗、维生素等。本研究的目的是简要概括突发性感音神经性听力损失病因和治疗的现代观点,分析1991 - 1996年期间我们耳鼻喉科该疾病的病例,并将这些数据与其他作者的相同或类似数据进行比较。
在本研究中,使用了1991 - 1996年期间在苏博蒂察健康中心耳鼻喉科确诊为突发性感音神经性听力损失的患者的病历。有53例该诊断的患者。所有患者均在医院接受了活性药物的静脉输注治疗。在诊断过程中,所有患者均接受了全面的临床耳鼻喉科检查,采集了详细的病史,进行了声阻抗测试(鼓室图)和纯音听阈测定。进行了常规血液检查(包括血常规、血沉、血糖)和尿常规检查。有时我们要求进行颞骨X线检查(施勒尔位和斯滕弗斯位)。如有必要,还进行了短增量敏感指数(SISI)测试和卡哈特测试。在前庭症状表现更强烈的病例中测试了前庭系统的功能。该测试在眩晕症状急性发作过后进行。入院后第七天和第十四天进行了对照听力测定。该治疗包括每天两次静脉输注250或500毫升生理溶液(氯化钠),其中加入300毫克烟酸占替诺安瓿、1克对乙酰氨基酚安瓿、10毫克双嘧达莫安瓿和10% 500毫克维生素C安瓿。对乙酰氨基酚和烟酸占替诺安瓿的数量在第14天增加,然后降至起始值。治疗持续17天。患者接受了口服多种维生素治疗、使用了镇静剂,并遵循无咖啡、无吸烟和无致敏食物的饮食。
该研究纳入了53例患者,其中女性27例(50.94%),男性26例(49.06%)(图1)。他们的年龄(图2)在16 - 71岁之间。最大的患者群体年龄在40 - 49岁(39.62%)。每年的分布情况(图3)表明,急性感音神经性听力损失的发病率与其他作者的研究结果不同,特别是在1991 - 1994年期间,因为病例很少。图4显示了这种疾病与季节的关系。我们在夏季(8月,16.98%)病例最多。冬季(12月,13.21%)略有上升。图5显示了以分贝为单位的听力损失程度。大多数患者(75.47%)有轻度或重度听力受损(40 - 85分贝)。患者入院前耳聋的时间在图7中显示。他们中的大多数在经历急性耳聋后的头七天内前来就诊(52.83%)。急性听力损失患者的症状学见表1。他们都有耳聋的感觉,50.94%的患者也有耳鸣。表2显示,在前庭冷热试验中只有两名患者有病理发现(功能减退)。通过这种方法测试的患者中有57.14%显示前庭装置功能正常。听力的恢复情况……