• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

儿童跌倒后神经功能预后的早期预测:代谢和临床标志物

Early prediction of neurological outcome after falls in children: metabolic and clinical markers.

作者信息

Paret G, Tirosh R, Lotan D, Stein M, Ben-Abraham R, Vardi A, Harel R, Barzilay Z

机构信息

Pediatric Intensive Care Unit, Chaim Sheba Medical Center, Tel Hashomer, Israel.

出版信息

J Accid Emerg Med. 1999 May;16(3):186-8. doi: 10.1136/emj.16.3.186.

DOI:10.1136/emj.16.3.186
PMID:10353044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1343331/
Abstract

Falls are the foremost reason for non-fatal injuries and are second only to motor vehicle accidents in causing accidental death. The purpose of this study was to identify the clinical and metabolic predictors of the outcome of head injury caused by falls from a height. Medical records of 61 children who had been admitted to the paediatric intensive care unit from 1990 to 1993 after falling from a height were reviewed retrospectively. Outcomes were categorised as good, moderate, severe, and poor. Glasgow coma scores, pupillary responses, brain oedema, and midline shift are significantly associated with poor outcome (p < 0.05). Metabolic markers associated with poor outcome included hyperglycaemia and hypokalaemia. Children with a poor outcome had, at admission, significantly higher glucose concentrations compared with children with good outcomes (mean SD): 20.0 (7.1) v 9.31 (4.0) mmol/l, p < 0.01), and lower potassium concentrations compared with children with good, moderate, and severe outcomes (mean (SD): 2.8 (0.4) v 3.7 (0.4) mmol/l, p < 0.001, 3.5 (0.3) mmol/l, p < 0.01, and 3.41 (0.3) mmol/l, p < 0.05, respectively). These findings allow for an early allocation of effort and resources to children injured from such falls.

摘要

跌倒是非致命伤害的首要原因,在导致意外死亡方面仅次于机动车事故。本研究的目的是确定高处坠落所致头部损伤结局的临床和代谢预测因素。回顾性分析了1990年至1993年期间因高处坠落入住儿科重症监护病房的61名儿童的病历。结局分为良好、中等、严重和差。格拉斯哥昏迷评分、瞳孔反应、脑水肿和中线移位与不良结局显著相关(p<0.05)。与不良结局相关的代谢指标包括高血糖和低钾血症。结局差的儿童在入院时的血糖浓度显著高于结局良好的儿童(均数±标准差):20.0(7.1)vs 9.31(4.0)mmol/L,p<0.01),与结局良好、中等和严重的儿童相比,钾浓度更低(均数(标准差):2.8(0.4)vs 3.7(0.4)mmol/L,p<0.001;3.5(0.3)mmol/L,p<0.01;3.41(0.3)mmol/L,p<0.05)。这些发现有助于早期为因此类坠落受伤的儿童分配精力和资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a2/1343331/5301ad0d4dae/jaccidem00030-0025-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a2/1343331/d7983d3be0d9/jaccidem00030-0025-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a2/1343331/5301ad0d4dae/jaccidem00030-0025-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a2/1343331/d7983d3be0d9/jaccidem00030-0025-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a2/1343331/5301ad0d4dae/jaccidem00030-0025-b.jpg

相似文献

1
Early prediction of neurological outcome after falls in children: metabolic and clinical markers.儿童跌倒后神经功能预后的早期预测:代谢和临床标志物
J Accid Emerg Med. 1999 May;16(3):186-8. doi: 10.1136/emj.16.3.186.
2
[Head injuries in children--clinical characteristics as prognostic factors].
Harefuah. 1999 May 2;136(9):677-81, 755.
3
Prognostic implications of hyperglycaemia in paediatric head injury.小儿颅脑损伤中高血糖的预后意义
Childs Nerv Syst. 1998 Sep;14(9):455-9. doi: 10.1007/s003810050259.
4
A retrospective review of paediatric head injuries in Asia - a Pan Asian Trauma Outcomes Study (PATOS) collaboration.一项关于亚洲儿童头部损伤的回顾性研究——泛亚创伤结局研究(PATOS)合作项目。
BMJ Open. 2017 Aug 18;7(8):e015759. doi: 10.1136/bmjopen-2016-015759.
5
Childhood head injury: causes, outcome, and outcome predictors. A Nigerian perspective.儿童头部损伤:病因、结局及结局预测因素。尼日利亚视角。
Pediatr Surg Int. 2004 May;20(5):348-52. doi: 10.1007/s00383-004-1196-5. Epub 2004 Jun 4.
6
Hyperglycemia: an independent risk factor for poor outcome in children with traumatic brain injury*.高血糖:创伤性脑损伤患儿预后不良的独立危险因素*
Pediatr Crit Care Med. 2014 Sep;15(7):623-31. doi: 10.1097/PCC.0000000000000170.
7
The motor response to stimulation predicts outcome as well as the full Glasgow Coma Scale in children with severe head injury.刺激引发的运动反应可预测预后,与儿童严重颅脑损伤的格拉斯哥昏迷量表(Glasgow Coma Scale)一样准确。
Pediatr Crit Care Med. 2010 May;11(3):339-42. doi: 10.1097/PCC.0b013e3181c014ab.
8
Initial neurologic presentation in young children sustaining inflicted and unintentional fatal head injuries.遭受故意伤害和意外致命性头部损伤的幼儿的初始神经学表现。
Pediatrics. 2005 Jul;116(1):180-4. doi: 10.1542/peds.2004-2671.
9
[Early predictors of outcome in children with head injuries].
Lijec Vjesn. 1993 Jul-Aug;115(7-8):224-9.
10
Head injuries from falls in preschool children.学龄前儿童跌倒所致头部损伤。
Yonsei Med J. 2004 Apr 30;45(2):229-32. doi: 10.3349/ymj.2004.45.2.229.

引用本文的文献

1
Hyperglycemia in critically ill children.危重症儿童的高血糖症
Indian J Crit Care Med. 2014 Jan;18(1):8-13. doi: 10.4103/0972-5229.125427.
2
Relationship between hyperglycemia and outcome in children with severe traumatic brain injury.严重创伤性脑损伤患儿的高血糖与预后的关系。
Pediatr Crit Care Med. 2012 Jan;13(1):85-91. doi: 10.1097/PCC.0b013e3182192c30.
3
Control of hyperglycaemia in paediatric intensive care (CHiP): study protocol.儿科重症监护中高血糖的控制(CHiP):研究方案。

本文引用的文献

1
Timing of paediatric deaths after trauma.创伤后儿科死亡的时间
BMJ. 1997 Mar 22;314(7084):868. doi: 10.1136/bmj.314.7084.868.
2
Risk of dying after a free fall from height.从高处自由落体后的死亡风险。
Forensic Sci Int. 1996 Apr 23;78(3):187-91. doi: 10.1016/0379-0738(95)01885-9.
3
Hyperglycemia is not a poor prognostic sign in head-injured children.高血糖并非头部受伤儿童预后不良的迹象。
BMC Pediatr. 2010 Feb 5;10:5. doi: 10.1186/1471-2431-10-5.
J Trauma. 1988 Apr;28(4):517-9. doi: 10.1097/00005373-198804000-00017.
4
The influence of dextrose administration on neurologic outcome after temporary spinal cord ischemia in the rabbit.葡萄糖给药对兔短暂性脊髓缺血后神经功能结局的影响。
Anesthesiology. 1989 Jan;70(1):64-70. doi: 10.1097/00000542-198901000-00014.
5
The mortality of childhood falls.
J Trauma. 1989 Sep;29(9):1273-5. doi: 10.1097/00005373-198909000-00015.
6
Hypokalaemia in severe head trauma.
Acta Neurochir (Wien). 1989;97(1-2):62-6. doi: 10.1007/BF01577741.
7
Elevated initial blood glucose levels and poor outcome following severe brain injuries in children.儿童严重脑损伤后初始血糖水平升高与预后不良。
J Trauma. 1991 Oct;31(10):1356-62. doi: 10.1097/00005373-199110000-00007.
8
Hyperglycemia and neurological outcome in patients with head injury.颅脑损伤患者的高血糖与神经功能结局
J Neurosurg. 1991 Oct;75(4):545-51. doi: 10.3171/jns.1991.75.4.0545.
9
Hypokalemia in resuscitation from multiple trauma.多发伤复苏中的低钾血症
Surg Gynecol Obstet. 1978 Jul;147(1):18-20.
10
Assessment of outcome after severe brain damage.重度脑损伤后结局的评估。
Lancet. 1975 Mar 1;1(7905):480-4. doi: 10.1016/s0140-6736(75)92830-5.