从艾滋病患者鼻咽部分离出新型隐球菌。
Recovery of Cryptococcus neoformans from the nasopharynx of AIDS patients.
作者信息
Sukroongreung S, Eampokalap B, Tansuphaswadikul S, Nilakul C, Tantimavanich S
机构信息
Department of Clinical Microbiology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand.
出版信息
Mycopathologia. 1998;143(3):131-4. doi: 10.1023/a:1006909532185.
Nasopharyngeal swabbings, obtained from AIDS patients, were plated onto Niger seed agar containing antibiotics Cryptococcus neoformans was isolated from 35 out of 84 patients (41.7%) diagnosed as primary cryptococcal cases before antifungal administration, and 8 out of 86 (9.3%) cryptococcosis patients on antifungal therapy. The fungus could not be isolated from any of 447 samples from 194 AIDS patients not diagnosed with cryptococcosis. These findings are novel in that the presence of C. neoformans in AIDS patients at this site has never been looked at previously.
从艾滋病患者身上采集鼻咽拭子，接种于含有抗生素的 Niger 种子琼脂平板上。在 84 例被诊断为原发性隐球菌病且尚未接受抗真菌治疗的患者中，有 35 例（41.7%）分离出新型隐球菌；在 86 例接受抗真菌治疗的隐球菌病患者中，有 8 例（9.3%）分离出该真菌。在 194 例未被诊断为隐球菌病的艾滋病患者的 447 份样本中，均未分离出该真菌。这些发现具有创新性，因为此前从未研究过艾滋病患者该部位是否存在新型隐球菌。
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