Nevéus T, Stenberg A, Läckgren G, Tuvemo T, Hetta J
Department of Pediatrics, Uppsala, Sweden.
Pediatrics. 1999 Jun;103(6 Pt 1):1193-7. doi: 10.1542/peds.103.6.1193.
To evaluate relationships between bladder voiding and sleep in children with enuresis.
Polysomnographic recordings were obtained from 25 children, aged 7 to 17 years, with monosymptomatic nocturnal enuresis. During 52 recorded nights, 37 enuretic events were detected. Responders (n = 7) and nonresponders (n = 16) to desmopressin treatment were compared.
The mean latency between sleep onset and the first bladder voiding was 3 hours 20 minutes (SD = 2 hours 5 minutes). The number of voidings were 19, 7, 10, and 1 occurring during stages 2, 3, and 4, and rapid-eye movement sleep, respectively. Desmopressin responders were found to void during the early or late part of the night, whereas the voidings of the nonresponders were dispersed evenly throughout the night (chi2 = 8.09).
The enuretic event is a predominantly non-rapid eye movement sleep phenomenon. Responders and nonresponders to desmopressin treatment void during different parts of the night.
评估遗尿症患儿膀胱排尿与睡眠之间的关系。
对25名年龄在7至17岁的单纯夜间遗尿症患儿进行多导睡眠图记录。在记录的52个夜晚中，检测到37次遗尿事件。比较去氨加压素治疗的反应者（n = 7）和无反应者（n = 16）。
入睡至首次膀胱排尿的平均潜伏期为3小时20分钟（标准差 = 2小时5分钟）。在第2、3、4阶段和快速眼动睡眠期间发生的排尿次数分别为19、7、10和1次。发现去氨加压素反应者在夜间早期或晚期排尿，而无反应者的排尿在整个夜间均匀分布（χ2 = 8.09）。
遗尿事件主要是非快速眼动睡眠现象。去氨加压素治疗的反应者和无反应者在夜间的不同时段排尿。
