Tosti A, Piraccini B M, D'Antuono A, Marzaduri S, Bettoli V
Department of Dermatology, University of Bologna, Via Massarenti 1, I-40138 Bologna, Italy.
Br J Dermatol. 1999 Jun;140(6):1165-8. doi: 10.1046/j.1365-2133.1999.02883.x.
We report six HIV patients who developed painful periungual inflammation of several nails during treatment with the antiretroviral drugs indinavir and lamivudine. The lesions appeared 2-12 months after starting treatment. The occurrence of paronychia in HIV patients has recently been reported in two groups of patients receiving either indinavir or lamivudine. Dermatologists should be aware of this recently reported and probably not uncommon side-effect of antiretroviral treatment in order to avoid an invasive approach to the nail lesions.
我们报告了6例艾滋病病毒（HIV）患者，他们在接受抗逆转录病毒药物茚地那韦和拉米夫定治疗期间，多个指甲出现疼痛性甲周炎症。这些损害在开始治疗后2至12个月出现。最近在两组分别接受茚地那韦或拉米夫定治疗的患者中报告了HIV患者甲沟炎的发生情况。皮肤科医生应了解这种最近报道的、可能并不罕见的抗逆转录病毒治疗副作用，以避免对指甲损害采取侵入性治疗方法。
