Becker C R, Knez A, Jakobs T F, Aydemir S, Becker A, Schoepf U J, Bruening R, Haberl R, Reiser M F
Institute of Diagnostic Radiology, Ludwig-Maximilians University Munich, Klinikum Grosshadern, Germany.
Eur Radiol. 1999;9(4):620-4. doi: 10.1007/s003300050720.
To identify patients with increased risk of having coronary artery disease (CAD), electron-beam computed tomography (EBCT) was used for years for quantifying calcifications of the coronary arteries. The first direct comparison between EBCT and conventional CT was performed to determine the reliability of widely available conventional CT for the assessment of the coronary calcium score. Fifty male patients with suspected CAD were investigated with both modalities, EBCT and conventional 500-ms non-spiral partial scan CT. Scoring of the coronary calcification was performed according to the Agatston method. Forty-two of these patients underwent coronary angiography for the assessment of significant luminal narrowing. The correlation coefficient of the score values of both modalities was highly significant (r = 0.982, p < 0.001). The variability between the two modalities was 42%. Mean calcium score in patients with significant coronary luminal narrowing (n = 37) was 1104 +/- 1089 with EBCT and 1229 +/- 1327 with conventional CT. In patients without luminal narrowing (n = 5) mean calcium score was 73 +/- 57 with EBCT and 26 +/- 35 with conventional CT. Although images of the heart from conventional CT may suffer from cardiac motion artifacts, conventional CT has the potential to identify patients with CAD with accuracy similar to EBCT.
为了识别患冠状动脉疾病（CAD）风险增加的患者，多年来一直使用电子束计算机断层扫描（EBCT）来量化冠状动脉钙化情况。首次对EBCT和传统CT进行直接比较，以确定广泛应用的传统CT在评估冠状动脉钙化积分方面的可靠性。对50例疑似CAD的男性患者分别采用EBCT和传统的500毫秒非螺旋局部扫描CT这两种方式进行检查。根据阿加斯顿方法对冠状动脉钙化进行评分。其中42例患者接受了冠状动脉造影以评估显著的管腔狭窄情况。两种方式的评分值之间的相关系数非常显著（r = 0.982，p < 0.001）。两种方式之间的差异为42%。在有显著冠状动脉管腔狭窄的患者（n = 37）中，EBCT测得的平均钙化积分为1104±1089，传统CT测得的为1229±1327。在无管腔狭窄的患者（n = 5）中，EBCT测得的平均钙化积分为73±57，传统CT测得的为26±35。尽管传统CT的心脏图像可能受到心脏运动伪影的影响，但传统CT有潜力以与EBCT相似的准确性识别CAD患者。
