Yamane T, Iesaka Y, Goya M, Takahashi A, Fujiwara H, Hiraoka M
Cardiovascular Center, Tsuchiura Kyodo Hospital, Ibaraki, Japan.
J Cardiovasc Electrophysiol. 1999 Apr;10(4):529-37. doi: 10.1111/j.1540-8167.1999.tb00709.x.
Although a variety of ablation techniques have been developed in the treatment of atrioventricular nodal reentrant tachycardia (AVNRT), there have been few reports discussing the location of the optimal target site. Based on our early experiences, we hypothesized that radiofrequency (RF) current applied around the upper margin of the coronary sinus ostium (UCSO) results in the most effective and safe treatment of AVNRT.
To confirm our hypothesis, the efficacy of RF currents applied around the UCSO guided by local electrograms in 59 patients (group B: predetermined focal mapping approach) were compared with the outcomes in 60 other patients previously treated with the standard electrogram-guided mapping method starting around the lower margin of the coronary sinus ostium (group A). The precise location of ablation catheters at successful sites (S) was also evaluated. All the patients were successfully treated without complications. Significantly fewer RF pulses and lower energies were needed in group B patients (mean RF applications: 4.3 vs 1.4 applications, mean total energy delivered: 4,699 vs 2,236 J in groups A and B, respectively, P < 0.01). Detailed analyses of the anatomical locations of S using CS venography in group B patients who received only a single RF application (46 patients) revealed that the distance between His and S varied according to the length of Koch's triangle, while that between S and UCSO was relatively constant. In 85 % of these 46 patients, S was located within 5 mm above and below the level of the UCSO.
RF applications around the UCSO guided by local electrograms yielded excellent outcomes in AVNRT patients with wide varieties in the size of Koch's triangle. The optimal target site was located within 5 mm above and below the level of UCSO along the tricuspid annulus.
尽管在房室结折返性心动过速(AVNRT)的治疗中已开发出多种消融技术,但很少有报告讨论最佳靶点位置。基于我们早期的经验,我们推测在冠状窦口上缘(UCSO)周围施加射频(RF)电流可实现对AVNRT最有效且安全的治疗。
为证实我们的假设,将59例患者(B组:预定的局灶标测方法)在局部电图引导下于UCSO周围施加RF电流的疗效与另外60例先前采用从冠状窦口下缘开始的标准电图引导标测方法治疗的患者(A组)的结果进行了比较。还评估了消融导管在成功部位(S)的精确位置。所有患者均成功治疗且无并发症。B组患者所需的RF脉冲明显更少且能量更低(平均RF应用次数:A组为4.3次,B组为1.4次;平均总输送能量:A组和B组分别为4699 J和2236 J,P < 0.01)。对仅接受一次RF应用的B组患者(46例)使用冠状窦静脉造影对S的解剖位置进行的详细分析显示,希氏束与S之间的距离根据科赫三角的长度而变化,而S与UCSO之间的距离相对恒定。在这46例患者中的85%,S位于UCSO水平上下5 mm范围内。
在局部电图引导下于UCSO周围进行RF应用在科赫三角大小各异的AVNRT患者中产生了极佳的效果。最佳靶点位置位于沿三尖瓣环的UCSO水平上下5 mm范围内。