Caputo C, Forbes A, Frost F, Sinclair M I, Kunde T R, Hoy J F, Fairley C K
Department of Epidemiology and Preventive Medicine, Monash University, The Alfred Hospital, Victoria, Australia.
Epidemiol Infect. 1999 Apr;122(2):291-7. doi: 10.1017/s0950268899002058.
A cross-sectional serosurvey for markers of prior Cryptosporidium infection was conducted among homosexual or bisexual males infected with human immunodeficiency virus (HIV); of 262 individuals approached, 236 (90%) agreed to participate. Serological response to two Cryptosporidium antigens was measured using a Western blot assay. The intensity or detection of serological responses to two Cryptosporidium antigens was not associated with CD4 cell counts or tap water consumption. A number of sexual practices were related to increased serological response for only the 27-kDa marker, including having had sex within the past 2 years, having anal sex and having had a larger number of sex partners during the past 2 years. Attending a spa or sauna was related to serological response to both the 27-kDa and 17-kDa markers. Based on these results, activities related to sexual activity appear to be a significant risk factors for prior Cryptosporidium infection.
针对感染人类免疫缺陷病毒（HIV）的男同性恋或双性恋男性进行了一项关于既往隐孢子虫感染标志物的横断面血清学调查；在接触的262人中，236人（90%）同意参与。使用蛋白质印迹法检测对两种隐孢子虫抗原的血清学反应。对两种隐孢子虫抗原的血清学反应强度或检测结果与CD4细胞计数或自来水消费无关。一些性行为仅与27 kDa标志物的血清学反应增加有关，包括在过去2年内有过性行为、肛交以及在过去2年内有较多性伴侣。去过温泉浴场或桑拿浴室与对27 kDa和17 kDa标志物的血清学反应有关。基于这些结果，与性活动相关的行为似乎是既往隐孢子虫感染的重要危险因素。
