Horie Y, Kato M
Department of Pathology, Tottori University Hospital, Yonago, Japan.
Pathol Int. 1999 Feb;49(2):170-4. doi: 10.1046/j.1440-1827.1999.00841.x.
A case of pseudovascular squamous cell carcinoma in the uterine cervix of a 64-year-old woman was examined. Histologically, the lesion consisted of atypical, large, non-keratinizing squamous cells that exhibited not only acantholytic changes but also pseudovascular changes. Immunohistochemically, these tumor cells were positive for cytokeratin, epithelial membrane antigen and carcinoembryonic antigen, but none of them were positive for Factor VIII-related antigen or CD34. To our knowledge, pseudovascular carcinoma of the uterine cervix has not been described in the literature. Pathologists should be aware of this unusual form of cervical squamous cell carcinoma, particularly in the differential diagnosis of angiosarcoma.
对一名64岁女性子宫颈假性血管性鳞状细胞癌病例进行了检查。组织学上，病变由非典型的大的非角化鳞状细胞组成，这些细胞不仅表现出棘层松解改变，还表现出假性血管改变。免疫组化显示，这些肿瘤细胞细胞角蛋白、上皮膜抗原和癌胚抗原呈阳性，但均无因子VIII相关抗原或CD34呈阳性。据我们所知，子宫颈假性血管性癌在文献中尚未见报道。病理学家应意识到这种不寻常的子宫颈鳞状细胞癌形式，尤其是在血管肉瘤的鉴别诊断中。
