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宫颈微静脉型鳞状细胞癌:一种尚未被描述的鳞状细胞癌变异型。

Telangiectatic Squamous Cell Carcinoma of Uterine Cervix: A Previously Undescribed Variant of Squamous Cell Carcinoma.

出版信息

Int J Gynecol Pathol. 2020 Nov;39(6):595-598. doi: 10.1097/PGP.0000000000000644.

Abstract

Squamous cell carcinoma of the uterine cervix is the second most common malignancy in women worldwide. We describe an unusual telangiectatic variant of squamous cell carcinoma in a 53 yr old woman. The tumor showed the usual morphologic features of a poorly differentiated keratinizing squamous cell carcinoma with >75% tumor area showing cavernous hemangioma like ectatic spaces filled with blood. The blood-filled spaces lacked an endothelial lining as evidenced by negativity for CD31 and CD34. This unusual variant has not been reported previously. Awareness of this entity is necessary for avoiding confusion with vascular tumors such as hemangiomas and angiosarcoma.

摘要

子宫颈鳞状细胞癌是全球女性中第二大常见的恶性肿瘤。我们描述了一位 53 岁女性中一种不常见的毛细血管扩张型鳞状细胞癌变异型。肿瘤表现为低分化角化鳞状细胞癌的常见形态特征,超过 75%的肿瘤区域呈海绵状血管瘤样扩张腔隙,充满血液。充满血液的腔隙缺乏内皮衬里,CD31 和 CD34 均为阴性。这种不常见的变异型以前尚未报道过。了解这种病变对于避免与血管肿瘤(如血管瘤和血管肉瘤)混淆是必要的。

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