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癌症疼痛阿片类药物替代给药途径的成本建模

Cost modeling for alternate routes of administration of opioids for cancer pain.

作者信息

Hassenbusch S J

机构信息

Department of Neurosurgery, M. D. Anderson Cancer Center, Houston, Texas, USA.

出版信息

Oncology (Williston Park). 1999 May;13(5 Suppl 2):63-7.

PMID:10356701
Abstract

The economic considerations relative to neuraxial infusion can be looked at with different types of economic models, including cost-minimization, cost-effectiveness, and cost-benefit analyses. A theoretical predictive model was developed about 2 years ago using a computer spreadsheet and based on four levels of supportive data. The model shows that the breakeven point at which it becomes less expensive to administer opioids with an intrathecal/implanted pump, rather than an epidural/external pump, is between 3 and 6 months after the start of pain management. In addition, the break even point between systemic treatment and spinal delivery with an implanted system is between 1 1/2 and 2 1/2 years from start of pain treatment.

摘要

与神经轴内输注相关的经济考量可以通过不同类型的经济模型来审视,包括成本最小化、成本效益和成本效益分析。大约两年前,利用电子表格软件并基于四个支持性数据级别开发了一个理论预测模型。该模型显示,在疼痛管理开始后的3至6个月之间,使用鞘内/植入式泵而非硬膜外/外置泵给药阿片类药物的成本变得更低的盈亏平衡点。此外,从疼痛治疗开始起,全身治疗与植入式系统脊髓给药之间的盈亏平衡点在1.5至2.5年之间。

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