Stich V, Hejnová J, Sulkovicová H, Hainer V, Kunesová M
Oddĕlení tĕlovýchovného lékarství, Univerzita Karlova, Praha, Czech Republic.
Sb Lek. 1998;99(3):227-34.
Microdialysis--a technique available since more than two decades--has been recently applied in investigation of metabolism of adipose tissue in humans. The technique enables a continuous sampling of metabolites and other small molecules in the extracellular space of subcutaneous adipose tissue and it enables a local exposure of adipose tissue to metabolically active agents. The method has been used to determine the interstitial concentrations of metabolites (glycerol, glucose, lactate etc.) in adipose tissue and to investigate the regulation of lipolysis and of carbohydrate metabolism in situ in subcutaneous adipose tissue. The method has been widely used in clinical research of adipose tissue and it is supposed to be used for continuous monitoring of metabolites in clinical practice.
微透析技术（一种二十多年前就已出现的技术）最近被应用于人体脂肪组织代谢的研究。该技术能够连续采集皮下脂肪组织细胞外空间中的代谢物和其他小分子，还能使脂肪组织局部暴露于具有代谢活性的物质中。该方法已用于测定脂肪组织中代谢物（甘油、葡萄糖、乳酸等）的间质浓度，并用于研究皮下脂肪组织中脂解作用和碳水化合物代谢的原位调节。该方法已广泛应用于脂肪组织的临床研究，并且有望在临床实践中用于代谢物的连续监测。
