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At last, direct evidence that lipoxygenases play a role in atherogenesis.
J Clin Invest. 1999 Jun;103(11):1487-8. doi: 10.1172/JCI7298.
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Essential roles of lipoxygenases in LDL oxidation and development of atherosclerosis.
Antioxid Redox Signal. 2005 Mar-Apr;7(3-4):425-31. doi: 10.1089/ars.2005.7.425.
3
The role of lipoxygenase-isoforms in atherogenesis.
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4
Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice.
J Clin Invest. 1999 Jun;103(11):1597-604. doi: 10.1172/JCI5897.
5
12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice.
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6
12/15-lipoxygenase, oxidative modification of LDL and atherogenesis.
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Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice.
Circulation. 2004 Oct 5;110(14):2024-31. doi: 10.1161/01.CIR.0000143628.37680.F6. Epub 2004 Sep 27.
10
Expression of 12/15-lipoxygenase attenuates intracellular lipid deposition during in vitro foam cell formation.
Arterioscler Thromb Vasc Biol. 2005 Apr;25(4):797-802. doi: 10.1161/01.ATV.0000157580.26858.2d. Epub 2005 Jan 27.

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Genetic variations in HSPA8 gene associated with coronary heart disease risk in a Chinese population.
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Insecticides and atherosclerosis.
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本文引用的文献

1
Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice.
J Clin Invest. 1999 Jun;103(11):1597-604. doi: 10.1172/JCI5897.
4
Antiatherogenic effects of the antioxidant BO-653 in three different animal models.
Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10123-8. doi: 10.1073/pnas.95.17.10123.
5
6
The role of 15-lipoxygenase in atherogenesis: pro- and antiatherogenic actions.
Curr Opin Lipidol. 1997 Apr;8(2):111-7. doi: 10.1097/00041433-199704000-00009.
8
Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis.
Circulation. 1997 Feb 18;95(4):1062-71. doi: 10.1161/01.cir.95.4.1062.
9
Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development.
J Clin Invest. 1996 Nov 15;98(10):2201-8. doi: 10.1172/JCI119029.

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