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良性食管狭窄的内镜扩张术:1043例手术报告

Endoscopic dilation of benign esophageal strictures: report on 1043 procedures.

作者信息

Pereira-Lima J C, Ramires R P, Zamin I, Cassal A P, Marroni C A, Mattos A A

机构信息

Department of Gastroenterology, Santa Casa University Hospital, Porto Alegre Medical School, Brazil.

出版信息

Am J Gastroenterol. 1999 Jun;94(6):1497-501. doi: 10.1111/j.1572-0241.1999.01061.x.

Abstract

OBJECTIVE

Endoscopic dilation is considered the best treatment for most cases of benign esophageal stricture, although the best dilation technique and the kind of stricture is the most amenable to treatment is still controversial. We report on our experience on a large series of patients treated by dilation without the aid of fluoroscopy and compare the results of this therapy among patients with strictures from different causes.

METHODS

Between 1992 and 1997, we performed 1043 dilation sessions on 153 patients. Treatment was considered adequate if the esophageal lumen could be dilated up to the size of a 42F catheter. If the stricture recurred after initial successful treatment, the stricture was dilated again up to a 42F catheter.

RESULTS

One hundred forty patients (96 men, 44 women; mean age, 54.1 yr) were followed-up for a mean of 20.5 months (4 to 62 months). Stricture's etiology was postsurgical in 80 patients, peptic in 37, caustic in 12, and from other causes in 11 patients. Adequate dilation was achieved in 93.5% of the patients (131 of 140). Patients with peptic strictures needed a median of three sessions to be adequately dilated during follow-up in comparison to five sessions among patients with postsurgical or caustic strictures (p = 0.07). There were four perforations, with one death (2.8% and 0.7% per patient and 0.4% and 0.1% per session, respectively).

CONCLUSIONS

Endoscopic dilation without the aid of fluoroscopy is safe and effective in relieving dysphagia caused by benign strictures of different causes, although repeated sessions are necessary because of stricture recurrence.

摘要

目的

内镜扩张被认为是大多数良性食管狭窄病例的最佳治疗方法,尽管最佳的扩张技术以及最适合治疗的狭窄类型仍存在争议。我们报告了一系列在无荧光透视辅助下进行扩张治疗的患者的经验,并比较了不同病因所致狭窄患者的治疗结果。

方法

1992年至1997年间,我们对153例患者进行了1043次扩张治疗。如果食管腔能够扩张至42F导管的大小,则认为治疗充分。如果在初次成功治疗后狭窄复发,则再次将狭窄扩张至42F导管大小。

结果

140例患者(96例男性,44例女性;平均年龄54.1岁)接受了平均20.5个月(4至62个月)的随访。狭窄病因中,80例为术后,37例为消化性,12例为腐蚀性,11例为其他原因。93.5%的患者(140例中的131例)实现了充分扩张。消化性狭窄患者在随访期间达到充分扩张所需的扩张次数中位数为3次,而术后或腐蚀性狭窄患者为5次(p = 0.07)。发生了4例穿孔,1例死亡(分别为每位患者2.8%和0.7%,每次治疗0.4%和0.1%)。

结论

在无荧光透视辅助下进行内镜扩张对于缓解不同病因所致良性狭窄引起的吞咽困难是安全有效的,尽管由于狭窄复发需要进行多次治疗。

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