Raymondi Ricardo, Pereira-Lima Júlio C, Valves Alexandro, Morales Gustavo F, Marques Daniela, Lopes César Vivian, Marroni Cláudio A
Department of Gastroenterology and Hepatology, Santa Casa University Hospital of the Porto Alegre School of Medical Sciences (FFFCMPA), Brazil.
Hepatogastroenterology. 2008 Jul-Aug;55(85):1342-8.
BACKGROUND/AIMS: To report a large series of patients with strictures from different etiologies who underwent dilation without fluoroscopy.
Between 1992 and 2005, 321 patients who underwent 2750 dilation sessions were entered in a database. Dysphagia score, cause and location of the stricture and diameter of the bougies were recorded in every session.
The mean follow-up period was 18.8 months. Stricture was postsurgical in 204 patients, peptic in 60, caustic in 13, postradiotherapy in 13, and from other causes in 31. Clinical response was achieved in 92% of the postsurgical patients; 84% of the caustic injuries; 81% of the peptic patients; and 58% of the radiation injuries (p < 0.05). Absence of dysphagia was obtained in 68, 38, 67 and 27% of these, respectively (p < 0.05). All groups showed a significant improvement in dysphagia score, and 98% of patients in whom a 45F catheter was inserted, achieved clinical response. There were 6 perforations, with 2 deaths.
Endoscopic dilation for benign esophageal strictures without fluoroscopy is safe and effective. Postsurgical patients show excellent results for dilation, and caustic and post-radiotherapy strictures have the worst response. A diameter of 45F is a satisfactory end-point for therapy in the majority of cases.
背景/目的:报告一系列病因各异的狭窄患者在无荧光镜引导下接受扩张治疗的情况。
1992年至2005年期间,321例患者接受了2750次扩张治疗,并被录入数据库。每次治疗均记录吞咽困难评分、狭窄的病因和部位以及扩张探条的直径。
平均随访期为18.8个月。204例患者的狭窄为术后所致,60例为消化性,13例为腐蚀性,13例为放疗后所致,31例为其他原因。术后患者中有92%取得临床缓解;腐蚀性损伤患者中有84%;消化性患者中有81%;放射性损伤患者中有58%(p<0.05)。这些患者中分别有68%、38%、67%和27%的患者吞咽困难消失(p<0.05)。所有组的吞咽困难评分均有显著改善,插入45F导管的患者中有98%取得临床缓解。发生6例穿孔,2例死亡。
无荧光镜引导下对良性食管狭窄进行内镜扩张安全有效。术后患者扩张效果极佳,腐蚀性和放疗后狭窄的反应最差。在大多数情况下,45F的直径是满意的治疗终点。