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[中非共和国蜱传虫媒病毒研究(1973 - 1974年)。杜格贝病毒、CHF/刚果病毒、乔斯病毒和班贾病毒的分离]

[Surgey of tick-borne arboviruses in the Central African Republic (1973-1974). Isolation of Dugbe, CHF/Congo, Jos and Bhanja viruses].

作者信息

Sureau P, Cornet J P, Germain M, Camicas J L, Robin Y

出版信息

Bull Soc Pathol Exot Filiales. 1976 Jan-Feb;69(1):28-33.

PMID:1036474
Abstract

As a complement of the study of the epidemiology of the arboviruses in Central Africa a survey of tick borne viruses has been done, in the Central African Republic, from December 1972 to June 1974; 15.103 ticks were collected, mainly from cattle at the slaughterhouses. They include: 10.085 Ambylomma variegatum, 4.113 Boophilus, 542 Rhipicephalus and 363 Hyalomma. From 892 monospecific pools inoculated into baby mice, 98 isolates of virus were obtained. Among the 57 isolates which have been fully identified (the identification of 41 other isolates is still in progress), 4 different serotypes of arbovirus have been found: Dugbe virus has been the most frequently found with 45 isolates from A. variegatum and I from B. decoloratus; this virus, previously isolated from human cases in Central African Republic in 1967 and 1970 has been isolated from a new human case in 1973. One isolate of CHF/Congo virus has been obtained from Hyalomma nitidum, but this virus has not yet been isolated from human beeings in C.A.R. The two other tick borne viruses isolated during this survey are Jos virus (9 isolates) and Bhanja virus (I isolate), all of them from A variegatum.

摘要

作为对中非虫媒病毒流行病学研究的补充,于1972年12月至1974年6月在中非共和国开展了一项蜱传病毒调查;共采集了15103只蜱,主要来自屠宰场的牛。其中包括:10085只杂色花蜱、4113只微小牛蜱、542只棕扇头蜱和363只璃眼蜱。将892个单一种类的蜱悬液接种到乳鼠体内,获得了98株病毒分离株。在已完全鉴定的57株分离株中(另外41株分离株的鉴定仍在进行中),发现了4种不同血清型的虫媒病毒:杜贝病毒最为常见,从杂色花蜱中分离出45株,从无色牛蜱中分离出1株;该病毒曾于1967年和1970年从中非共和国的人类病例中分离出来,1973年又从一例新的人类病例中分离得到。从光亮璃眼蜱中获得了1株刚果出血热病毒分离株,但尚未在中非共和国的人类中分离到该病毒。此次调查中分离出的另外两种蜱传病毒是乔斯病毒(9株分离株)和班贾病毒(1株分离株),均来自杂色花蜱。

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