乔斯病毒的基因组和抗原特征。
Genomic and antigenic characterization of Jos virus.
机构信息
Center for Infection and Immunity and WHO Collaborating Centre for Diagnostics, Surveillance and Immunotherapeutics for Emerging Infectious and Zoonotic Diseases, Mailman School of Public Health, Columbia University, New York, NY, USA.
Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
出版信息
J Gen Virol. 2012 Feb;93(Pt 2):293-298. doi: 10.1099/vir.0.035121-0. Epub 2011 Oct 12.
Abstract
Jos virus (JOSV), originally isolated in Jos, Nigeria in 1967, has remained unclassified despite cultivation in tissue culture, development of animal models of infection and implementation of seroprevalence surveys for infection. Here, we report genetic, ultrastructural and serological evidence that JOSV is an orthomyxovirus distinct from but phylogenetically related to viruses of the genus Thogotovirus.
摘要
乔斯病毒（JOSV）最初于 1967 年在尼日利亚乔斯分离得到，但尽管在组织培养中进行了培养、开发了感染动物模型并进行了血清流行率调查，该病毒仍未得到分类。在这里，我们报告了遗传、超微结构和血清学证据，表明 JOSV 是一种正粘病毒，与 Thogotovirus 属的病毒不同但具有系统发育关系。
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