Butenko A M
Med Parazitol (Mosk). 1996 Apr-Jun(2):40-5.
In 1978-1991 the USSR-Guinea Virological and Microbiological Laboratory functioned in Kindia, the Republic of Guinea. Arbovirus activity in this country was studied by a number of virologists and other specialists. Their personal contribution and achievements in this collaboration are reflected in the present paper. About 74,000 mosquitoes, 100,000 Ixodidae ticks, 1,500 wild birds, 2,700 bats, 106 monkeys, and 308 other mammals, 927 blood samples collected from febrile patients were examined in 1978-1989, using inoculation of new-born white mice. As a result of this work 127 strains of the following arboviruses were isolated: Chikungunia (1 strain), Dengue 2 (4), Saboya (7), Wesselsbron (1), Bunyamwera (4), M'Poko (5), Rift Valley Fever (6), CHF-Congo (9), Dugbe (22), Bhanja (6), Forecariah (2), Jos (26), Abadina (15), Kindia (2), Ark 6956 (1), Fomede (2), Bluetongue (9), Mossuril (2), AnK 6009 (1), and Kolente (2). Dengue 2, Wesselsbron, Bunyamwera, M'Poko, Kindia, Mossuril viruses were isolated from mosquitoes. Ixodidae ticks were sources for isolation of Chikungunia, Saboya, CCHF, Dugbe, Bhanja, Forecaciah, Jos, Abadina, Kindia, Ark 6956, Fomede, Bluetongue, and Kolente viruses. Saboya, RVF, Fomede, Kolente, AnK 6909 were isolated from bats (Chiroptera); Saboya, Abadina, and Bluetongue viruses from birds. One strain of Dugbe virus was originated from the brain of Cercopithecus patas. Bunyamwera and Abadina viruses were isolated from the blood of two febrile patients. Serological identification of many strains was kindly conducted at the Pasteur Institute, Dakar (J. P.Digoutte) and some at the YARU, USA (R. Shope). Kindia and Ark 6956 (Reovirus, gr. Palyam), Fomede (gr. Chobar Gorge), Forecariah (Bunyavirus, gr. Bhanja), Kolente (Rhabdovirus) were identified as an original type of Lagos bat virus. The results of seroepidemiological surveys are also presented.
1978年至1991年期间,苏联-几内亚病毒学和微生物学实验室在几内亚共和国金迪亚开展工作。该国的虫媒病毒活动由多位病毒学家和其他专家进行研究。他们在这一合作中的个人贡献和成就都体现在了本文中。1978年至1989年期间,使用新生小白鼠接种的方法,对约74000只蚊子、100000只硬蜱、1500只野生鸟类、2700只蝙蝠、106只猴子、308只其他哺乳动物以及927份发热患者的血样进行了检测。通过这项工作,分离出了127株以下虫媒病毒:基孔肯雅病毒(1株)、登革2型病毒(4株)、萨博亚病毒(7株)、韦塞尔斯布朗病毒(1株)、布尼亚姆韦拉病毒(4株)、姆波科病毒(5株)、裂谷热病毒(6株)、刚果克里米亚出血热病毒(9株)、杜贝病毒(22株)、班贾病毒(6株)、福雷卡里亚病毒(2株)、乔斯病毒(26株)、阿巴迪纳病毒(15株)、金迪亚病毒(2株)、阿克6956病毒(1株)、福梅德病毒(2株)、蓝舌病毒(9株)、莫苏里尔病毒(2株)、安克6009病毒(1株)和科伦特病毒(2株)。登革2型病毒、韦塞尔斯布朗病毒、布尼亚姆韦拉病毒、姆波科病毒、金迪亚病毒、莫苏里尔病毒是从蚊子中分离出来的。基孔肯雅病毒、萨博亚病毒、刚果克里米亚出血热病毒、杜贝病毒、班贾病毒、福雷卡里亚病毒(应为福雷卡里亚病毒拼写错误,原文为Forecaciah,正确为Forecariah)、乔斯病毒、阿巴迪纳病毒、金迪亚病毒、阿克6956病毒、福梅德病毒、蓝舌病毒和科伦特病毒的分离源是硬蜱。萨博亚病毒、裂谷热病毒、福梅德病毒、科伦特病毒、安克6909病毒(应为安克6009病毒拼写错误,原文为AnK 6909,正确为AnK 6009)是从蝙蝠(翼手目)中分离出来的;萨博亚病毒、阿巴迪纳病毒和蓝舌病毒是从鸟类中分离出来的。1株杜贝病毒源自赤猴的脑部。布尼亚姆韦拉病毒和阿巴迪纳病毒是从两名发热患者的血液中分离出来的。许多毒株的血清学鉴定由达喀尔巴斯德研究所的J.P.迪古特(J. P.Digoutte)友好地进行,部分在美国耶鲁大学蚊虫研究单位(YARU)由R.肖普(R. Shope)进行。金迪亚病毒和阿克6956病毒(呼肠孤病毒,帕利亚姆组)、福梅德病毒(乔巴尔峡谷组)、福雷卡里亚病毒(布尼亚病毒,班贾组)、科伦特病毒(弹状病毒)被鉴定为拉各斯蝙蝠病毒的原始类型。本文还展示了血清流行病学调查的结果。