González Avila G, Fajardo Rodríguez A
Departamento de Medicina Interna, Hospital de Oncología, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D. F. México.
Nutr Hosp. 1999 Mar-Apr;14(2):67-70.
To determine the utility of rutinary periodic replacement catheter of total parenteral nutrition (TPN) to prevent the incidence of catheter-related infection.
Cancer patients admitted between Jan. 1, 1996 and Dec. 31, 1997, to receive TNP, were eligible for enrollment in the study. Placed a chateter of poliuretane with double lumen each patient for Nutrition Department. Replacement catheters done over a guidewire after ten days, with or without infection sings. Rates of catheter-related infection were documented for de novo, and guidewire exchanged catheters and analyzed relative risk for infection.
Twenty catheter-related infections developed in 140 patients. When the rate of catheter-associated infection was determined for each type of catheterization, the replacement catheter had a high observed rate of infection than either de novo type (19.5% vs 7.8%; p = 0.027). We found that the risk of developing a catheter-related infection in a de novo catheter was significantly less (p < 0.01).
确定全胃肠外营养（TPN）常规定期更换导管预防导管相关感染发生率的效用。
1996年1月1日至1997年12月31日期间收治的接受TNP的癌症患者符合本研究入组条件。为每位患者在营养科放置一根双腔聚氨酯导管。10天后经导丝更换导管，无论有无感染迹象。记录初次置管、经导丝更换导管的导管相关感染发生率，并分析感染的相对风险。
140例患者发生20例导管相关感染。当确定每种置管类型的导管相关感染率时，更换导管的感染发生率高于初次置管类型（19.5%对7.8%；p = 0.027）。我们发现初次置管发生导管相关感染的风险显著更低（p < 0.01）。
