Rezola Solaun R, Sanzo Ollakarizketa J M
Servicio de Anatomía Patológica, Instituto Oncológico, San Sebastián.
Rev Clin Esp. 1999 Apr;199(4):208-14.
The incidence, trend and survival of lung cancer according to histologic types in Gipuzkoa area were studied.
The incidence of cases of lung cancer from 1983 and 1992 were studied. Cancers were classified into four major histologic groups.
A total of 1,815 tumors were diagnosed, 91.3% carcinomas, 0.4% non-epithelial tumors and 8.3% non-classified tumors. Among males, 45.5% were squamous carcinomas and among females, 49.7% adenocarcinomas. The male/female ratio of tumors has changed from 17.1/1 for the 1983-1984 period to 9.61/1 for the 1991-1992 period. Among males, a significant increase of small cell carcinomas, adenocarcinomas and large cell carcinomas was observed. Among females, a significant increase of adenocarcinomas was observed. Survival at 5 years ranged from 25.6% for the large cell carcinoma to 11.6% for the small cell carcinoma.
Among males the squamous carcinoma and small cell carcinoma predominated; among females, adenocarcinoma was the most common type. An increase of lung cancer in both genders was observed and for all histologic types, with the exception of squamous carcinoma in males, with a plateau since 1988. The prognosis is very poor, and worse for the small cell carcinoma.
对吉普斯夸地区肺癌的发病率、趋势及生存率按组织学类型进行了研究。
研究了1983年至1992年肺癌病例的发病率。癌症被分为四大组织学组。
共诊断出1815例肿瘤，其中91.3%为癌，0.4%为非上皮性肿瘤，8.3%为未分类肿瘤。男性中，45.5%为鳞状细胞癌；女性中，49.7%为腺癌。肿瘤的男女比例已从1983 - 1984年期间的17.1/1变为1991 - 1992年期间的9.61/1。男性中，小细胞癌、腺癌和大细胞癌显著增加。女性中，腺癌显著增加。5年生存率从大细胞癌的25.6%到小细胞癌的11.6%不等。
男性中鳞状细胞癌和小细胞癌占主导；女性中，腺癌是最常见类型。观察到男女肺癌均有增加，且所有组织学类型（男性鳞状细胞癌除外）自1988年以来呈平稳状态。预后非常差，小细胞癌更差。
