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[2004年至2017年西班牙卡斯特利翁省支气管源性癌的发病率及生存率演变。]

[Evolution of the incidence and survival of bronchogenic carcinoma in the province of Castellón (Spain) from 2004 to 2017.].

作者信息

Miravet Sorribes Luis Miguel, Montoliu Nebot Joaquín, Iradi Casal Antonio, Carrera Hueso Francisco Javier, Arnedo Pena Alberto

机构信息

Sección de Neumología y Servicio de Farmacia, Hospital Universitario de la Plana. Vila-real (Castellón). España.

Consorcio Hospitalario Provincial de Castellón. Castellón. España.

出版信息

Rev Esp Salud Publica. 2023 Jun 14;97:e202306050.

Abstract

OBJECTIVE

Bronchogenic carcinoma (BC) is the second most frequent worldwide and the most lethal tumour in both sexes. Its incidence varies not only among countries but also among different areas of the same country. So, the aim of this work was to analyse the evolution of its incidence and survival in the province of Castellón from 2004 to 2017 and to compare them with those of de rest of the country.

METHODS

A retrospective observational study was carried out from patients diagnosed with BC and registered in the Castellón Tumour Register from 2004 to 2017. Survival was estimated using the Kaplan-Meier method whereas to estimate the relationship among different variables both the chi-square and ANOVA test were used.

RESULTS

4,346 cases were diagnosed, whose mean age was 67.5±11.3 years, 85.2% men, the most frequent histological types were adenocarcinoma (28.3%) and epidermoid carcinoma (25.1%). The gross global incidence was 53.4 cases/105 inhabitants, 90.9 cases/105 men and 15.7 cases/105 women. Median global survival at five years was 12.7%, 12% in men and 18.4% in women.

CONCLUSIONS

The global incidence of BC in Castellón is lower than the national one, having remained stable in men while it is double in women. Global survival at five years is less than 15%, being higher in women than in men, nevertheless it increases compared to that of previous studies.

摘要

目的

支气管源性癌(BC)是全球第二常见且男女中致死率最高的肿瘤。其发病率不仅在不同国家有所差异,在同一国家的不同地区也不尽相同。因此,本研究旨在分析2004年至2017年卡斯特利翁省BC发病率和生存率的变化情况,并与该国其他地区进行比较。

方法

对2004年至2017年在卡斯特利翁肿瘤登记处登记的BC确诊患者进行回顾性观察研究。采用Kaplan-Meier方法估计生存率,同时使用卡方检验和方差分析来评估不同变量之间的关系。

结果

共诊断出4346例病例,平均年龄为67.5±11.3岁,男性占85.2%,最常见的组织学类型为腺癌(28.3%)和表皮样癌(25.1%)。总体发病率为53.4例/10万居民,男性为90.9例/10万,女性为15.7例/10万。五年总体生存率中位数为12.7%,男性为12%,女性为18.4%。

结论

卡斯特利翁省BC的总体发病率低于全国水平,男性发病率保持稳定,而女性发病率为男性的两倍。五年总体生存率低于15%,女性高于男性,不过与先前研究相比有所提高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e343/10558110/56b9724ccdca/1135-5727-resp-97-e202306050-g002.jpg

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