Yeung C Y
Arch Dis Child. 1976 Sep;51(9):686-90. doi: 10.1136/adc.51.9.686.
Twenty infants with neonatal meningitis were treated with systemic and lumbar intrathecal antibiotics upon initial diagnosis. Failure to sterilize the CSF in 2-3 days was associated with evidence of ventriculitis in these infants who were then treated with intraventricular antibiotics. 4 infants died, but only 2 of them may be regarded as treatment failure. It is suggested that many deaths from neonatal meningitis may be preventable by early detection and treatment of ventriculitis with intraventricular antibiotics.
20例新生儿脑膜炎患儿在初诊时接受了全身及鞘内注射抗生素治疗。2至3天内脑脊液未能除菌与这些患儿出现脑室炎迹象相关，随后对其使用了脑室内抗生素治疗。4例患儿死亡，但其中仅有2例可被视为治疗失败。有人提出，通过早期发现脑室炎并使用脑室内抗生素治疗，许多新生儿脑膜炎导致的死亡可能是可预防的。
