MacInnes J I, Desrosiers R
Department of Pathobiology, University of Guelph, Ontario.
Can J Vet Res. 1999 Apr;63(2):83-9.
In recent years, Actinobacillus suis, Haemophilus parasuis, and Streptococcus suis have emerged as important pathogens of swine, particularly in high health status herds. Their association with a wide range of serious clinical conditions and has given rise to the moniker "suis-ide diseases." These organisms are early colonizers and, for that reason, are difficult to control by management procedures such as segregated early weaning. Vaccination, serodiagnostic testing, and even serotyping are complicated by the presence of multiple serotypes, cross-reactive antigens, and the absence of clear markers for virulence. In this review, we discuss our current understanding of the pathogenesis, epidemiology, and management of the causative agents of the "suis-ide diseases" of swine.
近年来，猪放线杆菌、副猪嗜血杆菌和猪链球菌已成为猪的重要病原体，尤其是在健康状况良好的猪群中。它们与多种严重临床病症相关，因此有了“猪致死性疾病”这一称谓。这些微生物是早期定植菌，因此难以通过诸如隔离早期断奶等管理措施加以控制。由于存在多种血清型、交叉反应抗原以及缺乏明确的毒力标志物，疫苗接种、血清学诊断检测甚至血清分型都变得复杂起来。在本综述中，我们讨论了目前对猪“致死性疾病”病原体的发病机制、流行病学及管理的认识。
