Gottschalk M, Lebrun A, Wisselink H, Dubreuil J D, Smith H, Vecht U
Département de pathologie et microbiologie, Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec.
Can J Vet Res. 1998 Jan;62(1):75-9.
The production of muramidase-released protein (MRP), extracellular protein factor (EF) and hemolysin (suilysin) by 101 Canadian field strains of Streptococcus suis capsular type 2 is described. Most strains (72%) isolated from diseased pigs were MRP-EF- and only 1 strain was MRP+EF+. This strain was also the only 1 to produce the hemolysin. Thirteen strains (15%) were MRP+ EF- and only 3 strains were MRP* EF-. All the strains isolated from clinically healthy pigs as well as a bovine and 2 human isolates had a MRP-EF- phenotype. In addition, 7 strains (8%) had a MRPS phenotype, which had so far been described for S. suis capsular type 1. In conclusion, most Canadian field isolates of S. suis capsular type 2 tested in this study do not produce the virulence-related proteins described so far for this bacterial pathogen.
本文描述了101株加拿大2型猪链球菌田间分离株的溶菌酶释放蛋白（MRP）、细胞外蛋白因子（EF）和溶血素（猪链球菌溶血素）的产生情况。从患病猪分离出的大多数菌株（72%）为MRP-EF-，只有1株为MRP+EF+。该菌株也是唯一产生溶血素的菌株。13株（15%）为MRP+EF-，只有3株为MRP-EF+。从临床健康猪以及1株牛和2株人分离株中分离出的所有菌株均具有MRP-EF-表型。此外，7株（8%）具有MRPS表型，该表型迄今仅在1型猪链球菌中被描述过。总之，在本研究中测试的大多数加拿大2型猪链球菌田间分离株不产生迄今已报道的与该细菌病原体毒力相关的蛋白质。
