Kabasawa Y, Ishii A, Murata H, Takaoka M
Acta Allergol. 1976 Dec;31(6):442-54. doi: 10.1111/j.1398-9995.1976.tb01494.x.
Clinical studies were conducted to evaluate the role of the house dust mite. Dermatophagoides pteronyssinus, as an allergen in children's asthma in Japan. Skin testing and Prausnitz-Küstner type skin testing showed good correlations between the allergenicity of house dust and the mite. A positive Prausnitz-Küstner type skin reaction to house dust was neutralized by a mite extract. Radioallergosorbent test showed good correlation between house dust and the mite (r=0.687). The mite exhibited in vitro inhibition of radioallergosorbent test to house dust. The inhalation provocation test resulted in an acute respiratory attack in one of the patients. These results suggest that the house dust mite is an important allergen in asthmatic children in Japan.
开展了临床研究以评估屋尘螨（粉尘螨）作为变应原在日本儿童哮喘中的作用。皮肤试验和普劳斯尼茨－屈斯特纳氏型皮肤试验表明，屋尘和该螨的变应原性之间具有良好的相关性。对屋尘的阳性普劳斯尼茨－屈斯特纳氏型皮肤反应可被螨提取物中和。放射变应原吸附试验表明屋尘和该螨之间具有良好的相关性（r=0.687）。该螨在体外对屋尘的放射变应原吸附试验具有抑制作用。吸入激发试验导致一名患者发生急性呼吸道发作。这些结果提示，屋尘螨是日本哮喘儿童的一种重要变应原。
