Bourée P, Kouchner G, Gascon A
Bull Soc Pathol Exot Filiales. 1976 Mar-Apr;69(2):177-8.
A recent trichinosis epidemy involved around hundred patients in southern Paris suburbs; most frequent and marked clinical features were: facial and palpebral oedema, fever, bowel troubles (mostly constipation; diarrhea was seldom) and muscular tenderness. Most of the time eosinophiles cells and muscular enzymes were markedly raised. Trichinosis was proved by serological changes, with some delay. One muscular biopsy was found positive. Therapy consisted either in Thiabendazole (manufacturer's name: Mintezol) sometimes associated with prednisolone, or fluoromebendazole. There was no lethality.
最近在巴黎南郊发生了一起旋毛虫病疫情,涉及约百名患者;最常见且显著的临床特征为:面部和眼睑水肿、发热、肠道问题(大多为便秘;腹泻很少见)以及肌肉压痛。大多数情况下,嗜酸性粒细胞和肌肉酶显著升高。旋毛虫病通过血清学变化得到证实,但有一定延迟。有一次肌肉活检结果呈阳性。治疗方法包括使用噻苯达唑(商品名:Mintezol),有时联合泼尼松龙,或使用氟苯达唑。无一例死亡。