Bourée P, Bouvier J B, Passeron J, Galanaud P, Dormont J
Br Med J. 1979 Apr 21;1(6170):1047-9. doi: 10.1136/bmj.1.6170.1047.
A localised outbreak of trichinosis occurred in January 1976 in the southern suburbs of Paris. A total fo 125 cases was recorded including 30 children. The prominent symptoms were oedema of the face or eyelids, fever, and myalgia; diarrhoea was unusual and constipation common. An increased blood eosinophil count and raised serum concentrations of muscular enzymes strongly indicated trichinosis. This diagnosis was confirmed later immunologically. The parasite was found in only three out of 32 muscle biopsy specimens but this investigation was made relatively early in the disease. No deaths occurred. In all cases clinical recovery was fast and serum antibody titres were maximum during the first month and decreased slowly. The disease was milder and the recovery faster in children than adults. Epidemiological study suggested that horse meat was responsible for the infection, though no meat could be examined.
1976年1月，巴黎南郊发生了旋毛虫病局部暴发。共记录到125例病例，其中包括30名儿童。突出症状为面部或眼睑水肿、发热和肌痛；腹泻不常见，便秘常见。血液嗜酸性粒细胞计数增加和血清肌肉酶浓度升高强烈提示旋毛虫病。这一诊断后来通过免疫学得到证实。在32份肌肉活检标本中仅在3份中发现了寄生虫，但这项检查是在疾病相对早期进行的。无死亡病例。所有病例临床恢复迅速，血清抗体滴度在第一个月达到最高，然后缓慢下降。儿童的病情比成人轻，恢复也更快。流行病学研究表明，虽然无法对肉类进行检查，但感染是由马肉引起的。
