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[旋毛虫病。伊比利亚半岛一次大规模疫情的研究]

[Trichinosis. A study of a large outbreak on the Iberian peninsula].

作者信息

Cobo J, Gómez Cerezo J, Medraño J C, Zapico R, Cruz Martínez A, Molina F, Vázquez J J

机构信息

Servicio de Medicina Interna, Hospital La Paz, Madrid.

出版信息

An Med Interna. 1991 Sep;8(9):441-4.

PMID:1958779
Abstract

An epidemic outbreak of trichinosis after wild boar meat ingestion was analysed. The most frequent clinical manifestations were: muscular pain, fever, periorbitary edema and conjunctivitis. Laboratory tests showed eosinophilia and increased muscular enzymes. There was no mortality. 10 patients had electromyograms, which all showed an inflammatory myopathy pattern. The one fiber study showed similar signs as those found in cases of polymyositis. There was a significant statistical relationship between intensity and duration of symptoms in the intestinal phase and eosinophils levels in peripheral blood. There was also a statistically significant relationship between CPK levels and decrease of mean duration of motor unit potential. Treatment with thiabendazole and steroids was useful. The indirect immunofluorescence test (IIT) proved an excellent method for diagnosing trichinosis.

摘要

对一起食用野猪肉后爆发旋毛虫病的疫情进行了分析。最常见的临床表现为:肌肉疼痛、发热、眶周水肿和结膜炎。实验室检查显示嗜酸性粒细胞增多和肌肉酶升高。无死亡病例。10例患者进行了肌电图检查,均显示为炎性肌病模式。单纤维研究显示出与多发性肌炎病例中发现的相似体征。肠道期症状的强度和持续时间与外周血嗜酸性粒细胞水平之间存在显著的统计学关系。肌酸磷酸激酶(CPK)水平与运动单位电位平均持续时间的缩短之间也存在统计学上的显著关系。使用噻苯达唑和类固醇治疗有效。间接免疫荧光试验(IIT)被证明是诊断旋毛虫病的一种极好方法。

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