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恒河猴月状前回间半球间冲动传导的特征

Characteristics of interhemispheric impulse conduction between prelunate gyri of the rhesus monkey.

作者信息

Swadlow H A, Rosene D L, Waxman S G

出版信息

Exp Brain Res. 1978 Nov 15;33(3-4):455-67. doi: 10.1007/BF00235567.

DOI:10.1007/BF00235567
PMID:103739
Abstract

Cells of origin of the corpus callosum (callosal efferent neurons) in prelunate gyrus (area OA) of the rhesus monkey were studied using electrophysiological techniques. Monkeys were chronically prepared and callosal efferent neurons were identified by their antidromic activation following electrical stimulation of the contralateral prelunate gyrus and/or the splenium of the corpus callosum. Interhemispheric antidromic latencies ranged from 2.6--18.0 ms (median = 7.0 ms) while the conduction velocity along the length of the axon ranged from 2.8 to 22.5 M/s (median = 7.4 M/s) while the conduction velocity along the length of the axon ranged from 2.8 to 22.5 M/s (median = 7.4 M/s. Following the relative refractory period of a single prior impulse, all but one of 61 callosal efferent neurons studied showed a supernormal period of increased axonal conduction velocity and excitability. Following several prior impulses, the supernormal period was followed by a subnormal period of decreased axonal conduction velocity and excitability, which, depending on the number of prior impulses, lasted from several hundred ms to nearly 2 min.

摘要

采用电生理技术对恒河猴月状前回(OA区)胼胝体的起源细胞(胼胝体传出神经元)进行了研究。对猴子进行长期准备,通过电刺激对侧月状前回和/或胼胝体压部后逆向激活来识别胼胝体传出神经元。半球间逆向潜伏期为2.6 - 18.0毫秒(中位数 = 7.0毫秒),而沿轴突长度的传导速度为2.8至22.5米/秒(中位数 = 7.4米/秒)。在单个先前冲动的相对不应期之后,所研究的61个胼胝体传出神经元中,除一个外,其余均显示出轴突传导速度和兴奋性增加的超常期。在几个先前冲动之后,超常期之后是轴突传导速度和兴奋性降低的低常期,根据先前冲动的数量,低常期持续数百毫秒至近2分钟。

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