Lindholt J S, Vammen S, Juul S, Henneberg E W, Fasting H
Department of Vascular Surgery, Hospital of Viborg, Denmark.
Eur J Vasc Endovasc Surg. 1999 Jun;17(6):472-5. doi: 10.1053/ejvs.1999.0835.
the sensitivity and specificity of screening for abdominal aortic aneurysms (AAAs) with ultrasonographic scanning (US) is unknown. The aim of the study was to validate US as screening test for AAAs.
4176 (76.3%) of 5470 men aged 65-73 attended hospital-based US screening for an AAA at their local hospital. Two observers and one scanner were used. The maximal anterior-posterior (AP) of the dilated aorta, or 2 cm above the bifurcation, and at the crossing of left renal vein was recorded. In 50 cases, blinded measurements were carried out by two observers. An AAA was defined as an AP diameter greater than 29 mm.
the standard deviation (s.d.) of the interobserver variability of the distal AP diameter was 0.84. The mean distal AP diameter was 17. 9 mm (s.d. 2.92). Combining these data, the estimated diagnostic sensitivity was 98.9%, the estimated diagnostic specificity was 99. 9%. The interobserver s.d. of the proximal AP diameter was 1.76. The mean proximal AP diameter was 18.4 mm (s.d. 2.45). Combining these data, the estimated diagnostic sensitivity was 87.4%, the estimated diagnostic specificity was 99.9%.
US seems to be a valid screening method for AAA. Screening for proximal infrarenal aorta aneurysm remains acceptable because the majority of aortic diameters in this segment are so much smaller than the diameters that define an AAA.
超声扫描(US)筛查腹主动脉瘤(AAA)的敏感性和特异性尚不清楚。本研究的目的是验证US作为AAA筛查试验的有效性。
5470名年龄在65 - 73岁的男性中,有4176人(76.3%)在当地医院接受了基于医院的AAA超声筛查。使用了两名观察者和一台扫描仪。记录扩张主动脉的最大前后径(AP),或在分叉上方2 cm处以及左肾静脉交叉处的AP。在50例病例中,由两名观察者进行盲法测量。AAA定义为AP直径大于29 mm。
远端AP直径的观察者间变异标准差(s.d.)为0.84。远端AP平均直径为17.9 mm(s.d. 2.92)。综合这些数据,估计诊断敏感性为98.9%,估计诊断特异性为99.9%。近端AP直径的观察者间s.d.为1.76。近端AP平均直径为18.4 mm(s.d. 2.45)。综合这些数据,估计诊断敏感性为87.4%,估计诊断特异性为99.9%。
US似乎是一种有效的AAA筛查方法。对肾下主动脉近端动脉瘤进行筛查仍然是可行的,因为该节段的大多数主动脉直径远小于定义AAA的直径。