• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[Determination of basic drugs in blood by RP-HPLC].

作者信息

Zhuo X, Wu H, Liu W, Huang Z

机构信息

Institute of Forensic Sciences, Ministry of Justice, Shanghai.

出版信息

Fa Yi Xue Za Zhi. 1997;13(4):203-4, 253-4.

PMID:10375835
Abstract

A reversed-phase HPLC method for determination of phenothiazines and tricyclin antidepressants in whole blood was described. In this paper, a model 1090 HPLC with DAD and a zorbax ODS column was used. The mobile phase was methanol: water: tritely amine (75:24.7:0.3) with pH 7.5. Cyproheptadine was used as internal standard in this method. Blood samples were extracted with the solid-phase extraction method and the liquid-liquid method. This method is suitable in forensic toxicology analysis for basic drugs.

摘要

相似文献

1
[Determination of basic drugs in blood by RP-HPLC].
Fa Yi Xue Za Zhi. 1997;13(4):203-4, 253-4.
2
[Application of liquid chromatography coupled with mass spectrometry (LC/MS) to determine antidepressants in blood samples].液相色谱-质谱联用(LC/MS)在血液样本中抗抑郁药测定中的应用
Arch Med Sadowej Kryminol. 2008 Oct-Dec;58(4):171-6.
3
[Analysis of 37 drugs in whole blood by HPLC after solid phase extraction].
Fa Yi Xue Za Zhi. 2006 Oct 15;22(5):349-52.
4
[Systematic analysis of basic drugs in plasma using X-5 solid-phase extraction GC-FID and GC-MS].[采用X-5固相萃取-气相色谱-氢火焰离子化检测器和气相色谱-质谱联用技术对血浆中基本药物进行系统分析]
Yao Xue Xue Bao. 1996;31(4):296-9.
5
Atmospheric pressure ionization time-of-flight mass spectrometry coupled with fast liquid chromatography for quantitation and accurate mass measurement of five pharmaceutical drugs in human plasma.大气压电离飞行时间质谱联用快速液相色谱法用于定量测定和精确质量测定人血浆中的五种药物。
J Mass Spectrom. 2000 Mar;35(3):423-31. doi: 10.1002/(SICI)1096-9888(200003)35:3<423::AID-JMS953>3.0.CO;2-7.
6
Simple and simultaneous determination for 12 phenothiazines in human serum by reversed-phase high-performance liquid chromatography.反相高效液相色谱法同时简单测定人血清中的12种吩噻嗪类药物。
J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 1;854(1-2):116-20. doi: 10.1016/j.jchromb.2007.04.004. Epub 2007 Apr 13.
7
Simultaneous determination of the antipsychotic drugs levomepromazine and clozapine and their main metabolites in human plasma by a HPLC-UV method with solid-phase extraction.采用固相萃取-高效液相色谱-紫外检测法同时测定人血浆中抗精神病药物左美丙嗪和氯氮平及其主要代谢物。
J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Feb 1;846(1-2):273-80. doi: 10.1016/j.jchromb.2006.09.019. Epub 2006 Oct 12.
8
Extraction and determination of trace amounts of chlorpromazine in biological fluids using hollow fiber liquid phase microextraction followed by high-performance liquid chromatography.采用中空纤维液相微萃取结合高效液相色谱法萃取并测定生物流体中的痕量氯丙嗪。
J Pharm Biomed Anal. 2007 Dec 21;45(5):769-74. doi: 10.1016/j.jpba.2007.09.026. Epub 2007 Sep 29.
9
Microwave-assisted extraction of tricyclic antidepressants from human serum followed by high performance liquid chromatography determination.微波辅助从人血清中提取三环类抗抑郁药并随后进行高效液相色谱测定。
J Chromatogr A. 2008 May 9;1190(1-2):52-6. doi: 10.1016/j.chroma.2008.03.013. Epub 2008 Mar 18.
10
Development of an HPLC method for the monitoring of tricyclic antidepressants in biofluids.一种用于监测生物流体中三环类抗抑郁药的高效液相色谱法的开发。
J Sep Sci. 2007 Oct;30(15):2391-400. doi: 10.1002/jssc.200700142.