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[维生素B1的吸收。IV. 肠黏膜对35S-硫胺素吸收中巯基的水平]

[Vitamin B1 resorption. IV. Level of sulfhydryl groups in intestinal mucosa resorption of 35S-thiamine].

作者信息

Lazarov I

出版信息

Acta Vitaminol Enzymol. 1976;30(4-6):117-22.

PMID:1037629
Abstract

Studies have been carried on with the aim of investigating the effect of SH-groups on the absorption of 35S-thiamine in chicken's duodenum. The trial has been performed in chickens aged 56 days; as SH-groups releasing agents L-cysteine and SH-glutathion have been utilized; urea has been used in order to release SH-groups from protein molecules. The absorption of 35S-thiamine in duodenum is significantly increased in the presence of L-cysteine, SH-glutathion and urea. 35S-thiamine appears to be stored in the intestinal mucosa more conspicuously in the presence of urea. Concomitanly with the high levels of SH-groups in the duodenal mucosa, also the thiamine absorption results to be increased (P less than 0.001).

摘要

已开展多项研究,旨在探究巯基对鸡十二指肠中35S -硫胺素吸收的影响。试验在56日龄的鸡身上进行;使用了作为巯基释放剂的L -半胱氨酸和巯基谷胱甘肽;还使用了尿素以从蛋白质分子中释放巯基。在L -半胱氨酸、巯基谷胱甘肽和尿素存在的情况下,十二指肠中35S -硫胺素的吸收显著增加。在尿素存在的情况下,35S -硫胺素似乎更明显地储存在肠黏膜中。随着十二指肠黏膜中巯基水平的升高,硫胺素的吸收结果也会增加(P小于0.001)。

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