Chotinski D, Profirov Ia, Voĭnova R, Borisova L
Vet Med Nauki. 1987;24(6):48-51.
The effect of aflatoxin B1 on the content of SH-groups and the activity of leucinamino peptidase, Mg (Na+, K+), ATP, and glucoamylase in the mucous membrane of the small intestine of birds was studied. The experiment was carried out with three groups of male broilers. The controls were given starter and finisher mixtures with 21.6 and 19.5 per cent protein, with no aflatoxin B1. The birds of the test groups (II and III) were offered one and the same mixture containing 0.250 and 0.600 ppm of aflatoxin B1. By the end of the finisher period on the 49th day mucosa homogenate was used to determine the content of SH-groups and the activity of leucinamino peptidase, Mg (Na+, K+), ATP, and glucoamylase. It was found that rates of 0.600 ppm in the feed suppressed the activity of Mg (Na+, K+) ATP in the mucosa of the small intestine. Lower amounts (0.250 ppm) produced no effect on the activity of this enzyme. Leucinamino peptidase, glucoamylase, and the SH-groups did not change essentially their activity at the two rates of the toxin.
研究了黄曲霉毒素B1对鸟类小肠黏膜中SH基团含量以及亮氨酰氨基肽酶、Mg(Na +,K +)ATP酶和葡糖淀粉酶活性的影响。实验用三组雄性肉鸡进行。对照组给予蛋白质含量分别为21.6%和19.5%且不含黄曲霉毒素B1的起始料和育肥料混合物。试验组（II组和III组）的鸡饲喂含有0.250 ppm和0.600 ppm黄曲霉毒素B1的相同混合物。在第49天育肥期结束时，用黏膜匀浆测定SH基团含量以及亮氨酰氨基肽酶、Mg(Na +,K +)ATP酶和葡糖淀粉酶的活性。结果发现，饲料中0.600 ppm的添加量抑制了小肠黏膜中Mg(Na +,K +)ATP酶的活性。较低添加量（0.250 ppm）对该酶的活性没有影响。在两种毒素添加量下，亮氨酰氨基肽酶、葡糖淀粉酶和SH基团的活性基本没有变化。
