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[不同年龄喂食无维生素A饮食的大鼠中视黄醇-C14掺入的变化]

[Variations of retinol-C14 incorporation in rats of different ages fed a vitamin A-free diet].

作者信息

Carbini L, Dazzi E, Lantini T, Padalino A, Scarpa L A

出版信息

Acta Vitaminol Enzymol. 1976;30(4-6):146-51.

PMID:1037633
Abstract

Two groups of Wistar strain male albino rats of different age were treated with a large dose (300 I.U.) of vitamin A-acetate, after 24 h fasting. Each rat was then administered orally a single dose of 1,25mu C retinol-C14 to determine the rate of incorporation into different tissues. At intervals of 3 h and of 3, 6, 12 days the rats were killed; liver, kidney, blood, white fat tissue, brown fat tissue were taken and dried. Radioactivity was measured. The results show that in all tissue the mean percentage of incorporation, expressed in muC/g dry tissue, is generally higher in young than in adult rats.

摘要

两组不同年龄的Wistar品系雄性白化大鼠在禁食24小时后,用大剂量(300国际单位)的维生素A醋酸酯进行处理。然后给每只大鼠口服单剂量的1,25μC视黄醇-C14,以确定其掺入不同组织的速率。在3小时以及3天、6天、12天的间隔时间处死大鼠;取出肝脏、肾脏、血液、白色脂肪组织、棕色脂肪组织并干燥。测量放射性。结果表明,在所有组织中,以μC/克干组织表示的平均掺入百分比,幼鼠通常高于成年大鼠。

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