Redlin U, Vrang N, Mrosovsky N
Department of Zoology, University of Toronto, Ontario, Canada.
J Comp Physiol A. 1999 Apr;184(4):449-56. doi: 10.1007/s003590050344.
Syrian hamsters with intergeniculate leaflet or sham lesions were given tests with a series of light pulses of gradually decreasing intensities. The light pulses were given early in the night, at zeitgeber time 14-15. The amount of wheel running during the pulses was compared to that in the same hour on a night with no light pulses. Hamsters with intergeniculate leaflet lesions showed a significantly greater suppression of their wheel running in response to light than the sham-lesioned animals. The lesioned animals also had larger negative phase angles of entrainment to the 14:10-h light-dark cycle than sham-operated controls. However, phase shifting in response to light pulses at either zeitgeber time 14 or 18 was not significantly altered by the lesions. Preferences for spending more time in a dark than a light area were not abolished by the lesions. It is concluded that the intergeniculate leaflet in the Syrian hamster cannot be of paramount importance for masking of locomotor activity by light but may play a modulating role.
对具有膝间小叶损伤或假损伤的叙利亚仓鼠进行了一系列强度逐渐降低的光脉冲测试。光脉冲在夜间早期，即生物钟时间14至15时给予。将脉冲期间的跑步轮运动量与无光照脉冲的夜晚同一小时的运动量进行比较。与假损伤动物相比，具有膝间小叶损伤的仓鼠对光的反应表现出对跑步轮运动的显著更大抑制。损伤动物对14:10小时明暗循环的负向夹带相位角也比假手术对照组更大。然而，在生物钟时间14或18时对光脉冲的相位移动并未因损伤而发生显著改变。损伤并未消除在黑暗区域比在明亮区域花费更多时间的偏好。得出的结论是，叙利亚仓鼠的膝间小叶对于光对运动活动的掩盖并非至关重要，但可能起调节作用。
