Hardenbergh P H, Bentel G C, Prosnitz L R, Marks L B
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Semin Radiat Oncol. 1999 Jul;9(3):259-68. doi: 10.1016/s1053-4296(99)80018-6.
The role of locoregional radiation therapy after mastectomy is controversial. It reduces the risk of tumor relapse, improves breast cancer-specific survival and possibly overall survival, but has potential morbidity. This article reviews the technical aspects of postmastectomy radiation therapy and its associations with treatment-related morbidity. We consider common problems that arise in the technical setup of radiation fields. Adverse effects of postmastectomy radiation therapy may be reduced or prevented by careful radiation treatment planning.
乳房切除术后局部区域放射治疗的作用存在争议。它可降低肿瘤复发风险，提高乳腺癌特异性生存率，甚至可能提高总生存率，但存在潜在的发病率。本文综述了乳房切除术后放射治疗的技术方面及其与治疗相关发病率的关联。我们考虑了放射野技术设置中出现的常见问题。通过精心的放射治疗计划，可减少或预防乳房切除术后放射治疗的不良反应。
