Wright Jean L, Parekh Arti
Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Suite 1440, 401 North Broadway, Baltimore, MD 21231, USA.
Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Suite 1440, 401 North Broadway, Baltimore, MD 21231, USA.
Surg Oncol Clin N Am. 2017 Jul;26(3):383-392. doi: 10.1016/j.soc.2017.01.010.
Although the use of postmastectomy radiation therapy (PMRT) is widely accepted in certain clinical situations, areas of controversy persist for some clinical scenarios. In addition, with significant shifts in the management of breast cancer, including omission of axillary nodal dissection in select sentinel node-positive patients and increased use of neoadjuvant chemotherapy, new clinical challenges have arisen regarding the role of PMRT. This article reviews the data to support current recommendations for postmastectomy radiation and explores areas of controversy and the studies that guide clinicians in these scenarios.
尽管在某些临床情况下，乳房切除术后放射治疗（PMRT）的应用已被广泛接受，但在一些临床场景中仍存在争议领域。此外，随着乳腺癌治疗方式的重大转变，包括在部分前哨淋巴结阳性患者中省略腋窝淋巴结清扫以及新辅助化疗使用的增加，关于PMRT的作用出现了新的临床挑战。本文回顾了支持当前乳房切除术后放疗建议的数据，并探讨了争议领域以及在这些场景中指导临床医生的研究。
