新生小鼠和人类的T细胞功能。
T-cell function in newborn mice and humans.
作者信息
Adkins B
机构信息
Dept of Microbiology and Immunology, University of Miami Medical School, Miami, FL 33136, USA.
出版信息
Immunol Today. 1999 Jul;20(7):330-5. doi: 10.1016/s0167-5699(99)01473-5.
Abstract
Neonates mount poor immune responses, and it has been assumed that neonatal T cells differ qualitatively from adult T cells. Here, Becky Adkins discusses this issue in the light of recent data indicating that T cells in neonates are developmentally mature in their capacity to mount protective Th1-type and cytotoxic T lymphocyte responses.
摘要
新生儿的免疫反应较弱，人们一直认为新生儿的T细胞在性质上与成人T细胞不同。在此，贝基·阿德金斯根据最近的数据讨论了这个问题，这些数据表明新生儿的T细胞在产生保护性Th1型和细胞毒性T淋巴细胞反应的能力方面在发育上是成熟的。
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