Isacson D, Olofsson C
Division of Pharmaceutical Services Research, University of Uppsala, Sweden.
Pharm World Sci. 1999 Apr;21(2):96-9. doi: 10.1023/a:1008626306770.
Cross-sectional survey.
The county of Malmöhus, with 817,000 inhabitants, in the far south of Sweden. All drugs handed in for destruction to the 65 pharmacies during one week in March 1996 were analysed.
92% of the packages were prescription drugs for human use, 7% were over-the-counter drugs, and 1% were for veterinary use. Slightly less than half (48%) had expired when they were handed in for destruction. 36% were unbroken when returned and another 18% of the packages were nearly full. A comparison between the drugs sent in for destruction and the drugs sold in the county gave a ratio of 0.030. Antineoplastic and immunosuppressive drugs, drugs for the respiratory system, antiparasitic products, and cardiovascular drugs were returned to a greater extent than other types of drugs. Drugs for the genito-urinary tract, sex hormones, and drugs for the alimentary tract were returned to a lesser extent. Extrapolated to a whole year the value of caseated drugs was estimated to 60 SEK (5.83 Br,) per person. The value of unbroken packages was 20 SEK (1.94 Br,) per person per year.
Although not all of the drugs handed in for destruction could have been unnecessarily prescribed or obtained by the patient, a more cautious approach to prescribing of drugs would likely yield significant savings.
横断面调查。
瑞典最南部的马尔默胡斯县，有81.7万居民。对1996年3月某一周内提交给65家药店销毁的所有药品进行了分析。
92%的包装是人类处方药，7%是非处方药，1%是兽用药品。提交销毁时，略少于一半（48%）的药品已过期。归还时36%的药品包装未破损，另有18%的包装几乎是满的。提交销毁的药品与该县销售的药品之比为0.030。抗肿瘤和免疫抑制药物、呼吸系统药物、抗寄生虫产品以及心血管药物的归还比例高于其他类型的药物。泌尿生殖道药物、性激素和消化道药物的归还比例较低。推算到一整年，估计每人的报废药品价值为60瑞典克朗（5.83英镑）。未破损包装的价值为每人每年20瑞典克朗（1.94英镑）。
尽管并非所有提交销毁的药品都可能是患者不必要地开具或获取的，但更谨慎的开药方式可能会节省大量费用。
