Vogler Sabine, Leopold Christine, Zuidberg Christel, Habl Claudia
WHO Collaborating Centre for Pharmaceutical Pricing and Reimbursement Policies, Health Economics Department, Gesundheit Österreich GmbH/Geschäftsbereich ÖBIG - Austrian Health Institute, Vienna, Austria.
WHO Collaborating Centre for Pharmaceutical Pricing and Reimbursement Policies, Health Economics Department, Gesundheit Österreich GmbH/Geschäftsbereich ÖBIG - Austrian Health Institute, Vienna, Austria ; WHO Collaborating Centre for Pharmaceutical Policy and Regulation, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
J Pharm Policy Pract. 2014 Jun 11;7:6. doi: 10.1186/2052-3211-7-6. eCollection 2014.
To analyze a sample of pharmaceutical waste drawn from household garbage in Vienna, with the aim to learn whether and which medicines end up unused in normal household waste.
We obtained a pharmaceutical waste sample from the Vienna Municipal Waste Department. This was drawn by their staff in a representative search in October and November 2009. We did a manual investigation of the sample which contained packs and loose blisters, excluded medical devices and traced loose blisters back to medicines packs. We reported information on the prescription status, origin, therapeutic group, dose form, contents and expiry date. We performed descriptive statistics for the total data set and for sub-groups (e.g. items still containing some of original content).
In total, 152 packs were identified, of which the majority was prescription-only medicines (74%). Cardiovascular medicines accounted for the highest share (24%). 87% of the packs were in oral form. 95% of the packs had not expired. 14.5% of the total data set contained contents but the range of content left in the packs varied. Results on the packs with contents differed from the total: the shares of Over-the Counter medicines (36%), of medicines of the respiratory system (18%) and of the musculo-skeletal system (18%), for dermal use (23%) and of expired medicines (19%) were higher compared to the full data set.
The study showed that some medicines end up unused or partially used in normal household garbage in Vienna. Our results did not confirm speculations about a high percentage of unused medicines improperly discarded. There is room for improved patient information and counseling to enhance medication adherence and a proper discharge of medicines.
分析从维也纳家庭垃圾中抽取的一批药品废弃物样本,旨在了解是否以及哪些药品最终未被使用而进入普通家庭垃圾。
我们从维也纳市垃圾处理部门获取了一批药品废弃物样本。该样本由其工作人员在2009年10月和11月进行的一次具有代表性的搜索中抽取。我们对包含包装和散装水泡眼包装的样本进行了人工调查,排除了医疗设备,并将散装水泡眼包装追溯到药品包装。我们报告了有关处方状态、来源、治疗类别、剂型、成分和有效期的信息。我们对整个数据集和子组(例如仍含有一些原始成分的物品)进行了描述性统计。
总共识别出152个包装,其中大多数是仅凭处方销售的药品(74%)。心血管药物占比最高(24%)。87%的包装为口服剂型。95%的包装未过期。整个数据集中14.5%的包装含有药品成分,但各包装中剩余的含量范围各不相同。含有药品成分的包装的结果与总体情况不同:与整个数据集相比,非处方药的占比(36%)、呼吸系统药物的占比(18%)、肌肉骨骼系统药物的占比(18%)、皮肤用药的占比(23%)以及过期药品的占比(19%)更高。
该研究表明,在维也纳,一些药品最终未被使用或部分使用就进入了普通家庭垃圾。我们的结果并未证实关于大量未使用药品被不当丢弃的猜测。在改善患者信息和咨询以提高用药依从性以及正确处理药品方面仍有改进空间。