Tinazzi M, Frasson E, Bertolasi L, Fiaschi A, Aglioti S
Dipartimento di Scienze Neurologiche e della Visione, Sez. di Neurologia, Verona, Italy.
Neuroreport. 1999 May 14;10(7):1547-50. doi: 10.1097/00001756-199905140-00028.
Clinical and experimental evidence documents abnormal somatosensory functions in dystonia. Despite the fact that somatosensory processing is inherently temporal, mainly spatial aspects of somatosensory functions have so far been assessed in dystonic patients. Seven patients with idiopathic dystonia and nine healthy controls were given pairs of non-noxious electrical stimuli separated by different time intervals and asked to report if they perceived single or double stimuli. Somesthetic temporal discrimination thresholds (STDT) were obtained by computing the shortest time interval at which stimuli, applied to the left or the right hand, were perceived as separate. STDT were significantly higher in dystonic than in controls thus showing for the first time that temporal and not only spatial somatosensory processing is altered in dystonia.
临床和实验证据证明肌张力障碍存在异常的躯体感觉功能。尽管躯体感觉处理本质上具有时间性，但迄今为止，肌张力障碍患者的躯体感觉功能主要是从空间方面进行评估的。对7例特发性肌张力障碍患者和9名健康对照者施加间隔不同时间间隔的非伤害性电刺激对，并要求他们报告是否感觉到单个或双重刺激。通过计算施加于左手或右手的刺激被感知为分开的最短时间间隔来获得躯体感觉时间辨别阈值（STDT）。肌张力障碍患者的STDT显著高于对照组，从而首次表明肌张力障碍患者不仅在空间方面，而且在时间方面的躯体感觉处理都发生了改变。
