Cordick N, Parker L A, Ossenkopp K P
Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada.
Neuroreport. 1999 May 14;10(7):1557-9. doi: 10.1097/00001756-199905140-00030.
The taste reactivity test was used to evaluate the ability of motion sickness to produce conditioned rejection reactions, a putative measure of nausea in rats. Following three conditioning trials, rats displayed conditioned rejection reactions during an intraoral infusion of a rotation-paired saccharin solution. This is the first demonstration of conditioned rejection produced with a non-pharmacological emetic agent and provides support that the conditioned rejection reaction may serve as a rat model of nausea.
