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[留尼汪岛孕妇丙型肝炎病毒感染患病率]

[Prevalence of hepatitis C virus infection in pregnant woman on the island of Réunion].

作者信息

Faulques B, Michault A, Sevidjian B, Barau G, Pawlotsky J M, Dhumeaux D

机构信息

Service d'Hépato-Gastroentérologie, Centre Hospitalier Régional Sud Réunion, Saint-Pierre.

出版信息

Gastroenterol Clin Biol. 1999 Mar;23(3):355-8.

PMID:10384339
Abstract

AIMS

The aim of this prospective study was to assess the prevalence of anti-hepatitis C virus antibodies in a population of pregnant women in Réunion.

METHODS

Over a 6-month period, all blood samples of pregnant women who delivered at a hospital in the south of Réunion were tested with a third generation enzyme-linked immunoassay. In addition, risk factors for hepatitis C transmission were systematically looked for.

RESULTS

Among the 1,455 women tested during this period, only 2 sera were found to be positive, resulting in a prevalence of 0.14%. One of these women had a history of intravenous drug use, whereas the other had no identified risk factor. This low prevalence was found to be associated with a low frequency of risk factors of C virus infection in this population: a history of transfusion and intravenous drug use was found in 2.9% and 0.21% of cases, respectively.

CONCLUSIONS

The prevalence of hepatitis C virus infection is particularly low in Réunion. This low prevalence is explained by the rarity of risk factors for hepatitis C transmission in this region which is close to the African continent and has a similar high prevalence of hepatitis B virus infection.

摘要

目的

本前瞻性研究旨在评估留尼汪岛孕妇群体中抗丙型肝炎病毒抗体的流行情况。

方法

在6个月的时间里,对在留尼汪岛南部一家医院分娩的所有孕妇的血样进行第三代酶联免疫吸附测定检测。此外,系统地寻找丙型肝炎传播的危险因素。

结果

在此期间检测的1455名女性中,仅发现2份血清呈阳性,流行率为0.14%。其中一名女性有静脉吸毒史,而另一名女性未发现危险因素。发现这种低流行率与该人群中丙型肝炎病毒感染危险因素的低频率有关:分别有2.9%和0.21%的病例有输血史和静脉吸毒史。

结论

留尼汪岛丙型肝炎病毒感染的流行率特别低。这种低流行率是由于该地区靠近非洲大陆且乙型肝炎病毒感染流行率较高,丙型肝炎传播危险因素罕见所致。

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