Serme A K, Ilboudo P D, Samandoulgou A, Simpore J, Bougouma A, Sombie A R
Service d'hépato-gastroentérologie, centre hospitalier universitaire Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
Bull Soc Pathol Exot. 2006 May;99(2):108-9.
The aim of our study was to estimate the prevalence of Hepatitis C virus (HCV) among pregnant women and the rate of mother-child transmission. Over one month (April 26 to May 25, 2002) blood samples of 200 pregnant women who gave birth at the maternity of the university hospital and Gounguin center medical of Ouagadougou were tested for anti-HVC antibodies (Ac HCV) and anti HIV antibodies (Ac HIV). Infants born to mother tested positive for Ac HCV and their mother were tested for HCV-RNA. The prevalence of HCV (positive Ac HCV and HCV-RNA) was 2% in pregnant women (4/200). One case of mother-child transmission was found. The virus transmitted was 2a (A/C) genotype. The mother had a high titre of HCV-ARN, was co-infected by HIV and had had history of blood transfusion, excision and tattoo of the gums.
我们研究的目的是评估孕妇中丙型肝炎病毒（HCV）的流行率以及母婴传播率。在一个多月的时间里（2002年4月26日至5月25日），对在大学医院产科和瓦加杜古贡金中心医疗中心分娩的200名孕妇的血液样本进行了抗-HVC抗体（抗HCV）和抗HIV抗体（抗HIV）检测。母亲抗HCV检测呈阳性的婴儿及其母亲接受了HCV-RNA检测。孕妇中HCV（抗HCV和HCV-RNA呈阳性）的流行率为2%（4/200）。发现了1例母婴传播病例。传播的病毒为2a（A/C）基因型。母亲的HCV-ARN滴度很高，同时感染了HIV，并有输血、牙龈切除和纹身史。
